document_title: Guardians of the Galaxy: The Telltale Series

question_text: when is episode 4 of guardians of the galaxy coming out

question_tokens: when is episode 4 of guardians of the galaxy coming out

text: Guardians of the Galaxy: The Telltale Series

text: Gameplay[edit]

text: Guardians of the Galaxy plays similar to other Telltale games, in which the player's character talks to other characters, explore environments and interact with objects within it, and at times, complete action sequences made up of quick time events. Players make choices, such as dialog selection, that create determinants within the story affecting later actions within the episode and in future episodes. Within the series, the player primarily plays as Star-Lord, but may at times briefly take the role of another Guardian during action sequences, or, during specific times, play as another character in a flashback.[5]

text: Development[edit]

text: Telltale and Marvel partnered to develop the game, quickly establishing that they wanted to make an original story that used the character's canon but was not tied to the 2014 film. Telltale decided to go against an origins story, and instead focused on the connections between each of the five Guardians. Described by Marvel's Bil Rosemann, "A good Guardians story is about them as a family and showing how they're all misfits, they're all underdogs, they all feel like they don't have a family anymore" and coming together to form their own family that they depend on.[5] Telltale saw this as well as elements from the established character histories to find "potentially surprising" elements to include, according to Telltale producer Justin Lambros.[5] To achieve this, they planned each episode to center around each Guardian and explore their past, though the player will primarily remain in the role of Star-Lord throughout the series. This approach was novel for Telltale, since the character interactions that the player opts for in earlier episodes can have a stronger impact on the later episodes, particularly in the relationship between the other Guardians.[5] Telltale and Marvel's goal was to make the story accessible to people who may not have read through the comic series but had seen the film, while still dropping in hints and Easter eggs referring the Guardians' history in the comics to long-time fans.[5]

text: Telltale's Guardians was first revealed during the December 2016 Game Awards,[6] though rumors of the game had been previously found in material released by SAG-AFTRA actors as part of the 2016 video game voice actor strike in November.[7] The game's first of five episodes was released on April 18, 2017; in additional to digital downloads, a retail version will be available for the first episode release with an online pass to acquire the other episodes once released; this is expected to be released on May 2, 2017 in North America and May 5, 2017 in Europe.[8]

text: Telltale hosted a panel about the game at the 2017 PAX East event in Boston, MA in March 2017, as well as having the first episode available for a "crowd play" session during the 2017 South by Southwest event.[8]

text: Audio[edit]

text: The game is based on the Marvel Comic series and the recent film with an exclusive storyline. It has a different set of voice actors from the film. The cast currently includes Scott Porter as Star-Lord, Emily O'Brien as Gamora, Nolan North as Rocket Raccoon, Brandon Paul Eells as Drax the Destroyer, and Adam Harrington as Groot.[8]

text: Plot[edit]

text: Tangled Up in Blue[edit]

text: Peter Quill, AKA Star-Lord (Scott Porter) receives a distress-call from the Nova Corps, requesting the assistance of the Guardians of the Galaxy on an unidentified planet with an abandoned Kree outpost, where their forces are being decimated by the Mad Titan Thanos (Jake Hart). Arriving to reinforce the Nova Corps, the Guardians ship - the Milano - is shot down by Thanos' ship, causing it to crash-land on the planet. The Guardians survive and trek towards Thanos' location, with Rocket Raccoon (Nolan North) revealing he's constructed a new gun that can emit a highly powerful destructive force - at the cost of only having one shot. They discover Thanos has entered a large Kree building held shut by two metal doors, but Star-Lord is able to slip in through a fissure in the wall and blow it open from the inside using the canon from a crashed ship, finding the corpses of multiple Nova Corps members along the way. The Guardians then confront Thanos in the temple's lower chamber, who has obtained an ancient artifact called the Eternity Forge. The team struggles to defeat the tyrant and most become incapacitated, but Star-Lord manages to shoot Thanos in the chest with Rocket's new gun, successfully killing him. Star-Lord then takes the Eternity Forge from Thanos' hands, assuming it useless now that the danger has passed.

text: Following the battle, the Guardians celebrate their victory by spending the night at a bar in Knowhere, where Star-Lord interacts with his teammates now that their long-time foe is finally dead. He starts off with Drax the Destroyer (Brandon Paul Eells), who feels satisfied with Thanos' death as revenge for his family's murder by the mad tyrant. However, Rockets argue that Star-Lord was the one who killed Thanos with Groot (Adam Harrington) supporting him.

text:
If Star-Lord tells Drax the Destroyer that he earned his revenge, he states to Drax that he killed the one responsible for his family's death, satisfying Drax's need to atone for his family's death.
If Star-Lord doesn't tell Drax the Destroyer that he earned his revenge, he reminds him that he used Rocket Raccoon's gun on Thanos. This causes Drax to state that he would've expected this from Rocket Raccoon or Groot, promptly leaving after stating that he is not in the mood to celebrate.

text: Star-Lord than finds Rocket trying to show off the gun that killed Thanos to some of the bar-goers, bragging about being the brains behind the operation. Upon Star-Lord interacting with him, Rocket confesses that he's starting to feel burnt out by their life of constant chaos and near-death experiences, wishing to take a break on his own for a bit and even wondering if it's time for him to go his own way now that the Guardians no longer have to deal with Thanos. Afterwords, Star-Lord speaks with Gamora, who admits a small part of her wants to see her sister Nebula again - despite how angry the latter will be at learning she helped kill their adoptive "father" Thanos.

text:
If Star-Lord reminds Gamora that Nebula is still her sister, Gamora states that Star-Lord might be right and will consider calling her after a few more drinks. The two of them do a toast to family.
If Star-Lord tells Gamora to stay away from Nebula, he also tells Gamora that what Nebula doesn't know won't come back to kill them. Gamora states that it's a safe bet and wouldn't mind starting fresh. The two of them do a toast to moving on.

text: The next day, a hung-over Star-Lord wakes up to find the team amassed a large tab that they need to pay off and decide a good way to make money is to sell Thanos' body. Rocket suggests selling it to the Collector to get more credits, while Gamora thinks they should give the body to the Nova Corps so they don't have to deal with criminals. Both Gamora and Rocket Raccoon end up in an argument until Star-Lord breaks it up and that they will figure out who to sell Thanos' body to.

text:
If Star-Lord calls the Nova Corps to sell Thanos' body to them, he tells the female representative about it and takes in their bounty on him. After the call, Rocket gets angry and states that they would've gotten more units off of the Collector. The Guardians of the Galaxy will receive less of a paycheck and because the bounty has to go through a process, the money won't come to them until at least half a year.
If Star-Lord calls the Collector to sell Thanos' body to him, he talks with the Collector's representative Vylla (Erin Yvette) due to the conditions of Thanos' body, but manages to get their large share of space credits after some negotiation. Before ending the transmission, Vylla tells Star-Lord to make sure the body is there when she arrives with some associates. Gamora frustratedly states they are going down a dangerous path in dealing with the Collector.

text: After making a decision on who to sell Thanos' body to, Star-Lord suggests also selling the Eternity Forge for more credits and goes to retrieve it from his room, but the artifact starts to glow when he picks it up. Falling into a trance, Star-Lord experiences a flashback in which his mother Meredith Quill (Courtenay Taylor) gives a young Peter Quill (Jeremy Shada) advice on how to deal with bullies after one broke his walkman cassette player and having him promise to use his words instead of his fists in the future.

text:
If Peter Quill promises to use his words and not his fists, he tells his mother that he will. Meredith thanks her son. She also fixes Peter Quill's walkman as they listen to a song on it as a meteor shower occurs.
If Peter Quill can't hold on to that promise, he states that he doesn't know what will happen next time. Meredith tells Peter to try for her. She also fixes Peter Quill's walkman as they listen to a song on it as a meteor shower occurs.

text: As they watch the skies, Peter suddenly finds the Eternity Forge in his hands and hears his mother ask to "Come find me" - after which either Gamora or Rocket will snap Star-Lord out of it and tell him that he's been standing there for hours talking to the relic. Realizing the Eternity Forge isn't an inert trinket, Star-Lord decides not to sell it with Thanos' body.

text: After completing the trade of Thanos' body with whoever it was sold to, the team is attacked by Hala the Accuser (Faye Kingslee), her second-in-command Jyn-Xar (Chris Cox) and their small Kree army, demanding the Eternity Forge. During the chaotic battle, Hala manages to steal the Forge from Star-Lord and damage the Milano's engines before escaping back to the Kree's ship, the Revenant. Star-Lord than takes either Gamora or Drax with him in pursuit of Hala.

text:
If Star-Lord takes Gamora, she states they'll make their way through the ship with as little conflict as possible. Drax the Destroyer tells Star-Lord to kill all the Kree for him - and that he won't forgive him if any are left alive.
If Star-Lord takes Drax the Destroyer with him, Drax the Destroyer states that he shall be a violent worthy ally. Gamora tells Star-Lord not let Drax do anything stupid.

text: Star-Lord and his teammate arrive on the Kree ship, only to discover it barely operational with only a skeleton crew aboard - and a large assortment of preserved Kree corpses in stasis pods. Making their way to the bridge, the pair confront Hala the Accuser and learn the Eternity Forge can supposedly raise the dead, with Hala planning to resurrect her son Bal-Dinn and the rest of the Kree race after they and their entire planet were destroyed by Thanos - which will apparently require numerous "sacrifices" to accomplish. Hala than impales Star-Lord with her lance and incapacitates his teammate, though Rocket manages to intervene with the repaired Milano and blow out the bridge's windows before she can finish them. Star-Lord manages to reclaim the Eternity Forge as it is sucked out into space, while his teammate grabs him and carries him back to the Milano. As the team argues amongst themselves in panic over what to do, Star-Lord succumbs to his injuries.

text: While near-death, Peter Quill relives attending his mother's funeral as a boy and how he was adopted by Yondu (Mark Barbolak), who visited him in the chapel and revealed that Meredith entrusted him to watch over Peter Quill.

text:
If Peter trusts Yondu, he agrees to go along with Yondu who starts to show him his new home.
If Peter doesn't trust Yondu, this will cause Yondu to forcefully drag him to his new home.

text: Afterwards, the adult Peter finds himself hearing a knocking noise from his mother's casket and opens it, only to find his mother behind him. Placing her hand on his chest, Meredith tells Peter to come find her - while back in the present, the rest of the Guardians are left shocked as the Eternity Forge successfully heals Star-Lord's wound, bringing him back to life.

text: Under Pressure[edit]

text: After Star-Lord is revived, the rest of the Guardians are surprised and disbelieving at what the Eternity Forge did and thought he was possessed at first until he proves his identity. The Guardians are unsure on how the Eternity Forge could bring Star-Lord back to life, but Star-Lord can bring up how Hala mentioned the Forge could resurrect the Kree with enough "sacrifices" - allowing Drax the Destroyer to realize the Eternity Forge trades a life for a life, deducing it must absorbed Thanos' life-force when he died and than gave to Star-Lord to revive him. Just then, the Revenant catches up to the Milano, forcing them to take evasive maneuvers to escape. The Guardians suspect that Hala the Accuser plans on using the Eternity Forge to revive the dead Kree in her ship's stasis pods to create an unlimited army, re-establishing the Kree's empire. In order to lay low and for Rocket Racoon to fix the Milano, Star-Lord states that he knows someone who could help them out.

text: Heading to the planet Rajak in its Neon District, the Guardians arrive at a building where Star-Lord's surrogate father Yondu is living in seclusion. As Star-Lord introduces everyone to Yondu, he witnesses Rocket point his gun at Yondu, stating that he doesn't trust Ravagers. Yondu then has his telekinetic arrow pointed at Rocket in a tense stalemate.

text:
If Star-Lord asks Rocket what he is planning to do, Rocket states that Yondu's house is already a garbage heap as Star-Lord tells him not to blow Yondu and everyone inside to pieces.
If Star-Lord advises Yondu to put his arrow away, he also tells Yondu that Rocket has been sensitive that everyone is out to kill them. Yondu states that he can add them to the list.

text: Regardless of the choice, the two of them than start to laugh with Yondu revealing the two know each-other rather well, having been buying stuff from Rocket for years. After catching up, Star-Lord shows Yondu the Eternity Forge in hopes of learning more about it. When both of them touch the Eternity Forge, Star-Lord again flashes back to his childhood, where Meredith Quill tells the young Peter that he is meant for more of this life, claiming that he is going to save the galaxy, kill Thanos and change everything - something that surprises Peter as Meredith is describing things she wasn't even there to see. Meredith than asks Peter to sit with her and observe the stars.

text:
If Peter sits by his mother, he does so for just a minute.
If Peter doesn't sit by his mother, he claims that he is cool where he is.

text: As the two of them stare at the stars, Peter notices an hourglass-like constellation with the same shape as the Eternity Forge, with a series of patterns appearing across it that he doesn't recognize. Turning around, Peter realizes his mother is no longer there as he again hears call to "Come find me, Peter." After the flashback ends, Yondu comments that it's been decades since he has seen Meredith's face and the two wonder how she could be connected to the Eternity Forge. As Star-Lord looks over the relic again, glyphs appear over its surface that Gamora identifies as part of an ancient Kree language. While she can't translate it, Gamora thinks that Nebula might be able to, as the latter had taken something with similar markings for Thanos - though first they would have to find her and convince her to help, before Hala finds her.

text: As Yondu goes to obtain a device that would help repair the Milano, Rocket steps outside and Star-Lord goes to check up on him. As both of them go over what little they understand about the Eternity Forge's capabilities thus far, Rocket reveals that he hopes it can help him with someone he lost. Even though Rocket states he knows that Nebula is the top priority, he tells Star-Lord that they have to stop at Halfworld first so that, if nothing else, he can at least try to use the Eternity Forge. However, Gamora soon after reveals she's found out Nebula (Ashly Burch) has taken Thanos' ship and intends to recover his corpse from whoever the Guardians gave it to - if sold to the Collector, Nebula will be threatening the attendant within his museum for information on Star-Lord, before he and Gamora make their presence known; if sold to the Nova Corps, she will hijack one of their ships and make off with the body on Thanos' vessel, forcing the Milano into a space battle to capture Nebula before the Nova Corps kill her.

text:
If Star-Lord agrees to help Rocket, he tells the rest of the Guardians and Yondu that they will be making a detour to Halfworld. While displeased, Gamora reluctantly agrees to take the detour as Yondu warns Star-Lord to be careful with the newly repaired Milano. On Halfworld, Star-Lord and Rocket arrive outside the abandoned laboratory where Rocket was created, arriving at a grave that Rocket tries to use the Eternity Forge on. When that fails, Gamora tells Star-Lord that Nebula is tearing apart the place where Thanos' body is being held. By the time the Guardians catch up to Nebula and subdue her, she will have already secured Thanos' body and sent it to a place where she assures he'll receive a proper burial.
If Star-Lord doesn't agree to help Rocket, he tells Rocket that he wishes they could help but must find Nebula first. Rocket is not pleased with the answer and states that he will find his own way to get there. After Yondu fixes the Milano, Star-Lord tells Yondu that Rocket isn't here when asked for him to fire up the engines - only for the group to witness Rocket taking off in Yondu's ship, much to Yondu's dismay. Star-Lord reveals Rocket is going to Halfworld to take care of something as Yondu warns him to keep his group in line. Deciding to catch up with Rocket after they capture Nebula, the Guardians manage to intercept and capture Nebula before off before she can recover Thanos' body. Upon catching up to Rocket on Halfworld, Star-Lord is bitterly told by Rocket that he had his chance to help him and that the Forge didn't work.

text: In either case, when Star-Lord arrives on Halfworld and touches the Eternity Forge on Rocket Raccoon's hand after it fails to work for him, he suddenly experiences a flashback of Rocket Raccoon's past regarding his creation. In it, Rocket is placed in a cage across from the otter Lylla (Fryda Wolff) as the two of them plan their escape. As Rocket assembles a device to help them, he finds information that the scientists are going to eliminate Lylla. Unfortunately, as the two of them evade the robots, Rocket finds that one of the machines managed to land a lethal injection on Lylla. After sealing in the Halfworld scientist (Chris Cox) and the robots, Lylla opens the doors as she plans to take some of them down with her before the lethal injection kicks in, advising Rocket to leave while he has the chance.

text:
If Rocket honors Lylla's death wish, he says goodbye to Lylla and tells her to mess them up for the both of them, to which Lylla promises that she will. After Rocket escapes, he hears an explosion come from the laboratory and sees smoke emerge, mourning Lylla's death.
If Rocket carries Lylla out of the laboratory, both of them make it out into the open. He then places Lylla's body on the ground as she shares a moment outdoors with Rocket, fulfilling her desire to see the outside world before she dies in his arms.

text: After the memory experience ends, Rocket angrily tells Star-Lord that he had no right to see it, feeling violated at having his past revealed without his permission. Rocket than restores Lylla's grave, which Star-Lord can offer to help with or not, before they return to the Milano. Star-Lord than tries to devise a way to get Nebula's help in deciphering the ancient Kree language, with Gamora suggesting they offer Rocket repairing Nebula's damaged mechanical arm as leverage. Entering Gamora's room, which Nebula has been locked up in, Star-Lord and Gamora explain that they need her to translate the ancient Kree language, but Nebula is reluctant cooperate. When Nebula tells Gamora that she still remembers Tar-Voll, Gamora draws her sword on her as Nebula orders for Gamora to leave.

text:
If Star-Lord has Gamora leave, she does so while warning Star-Lord that she won't help him if she hears screams. Nebula than remarls that she never cared for them.
If Star-Lord agrees with Gamora, he states that Gamora has the right idea in thinking Nebula untrustworthy as he pins Nebula against the wall.

text: Drax the Destroyer later tells Star-Lord that there was a device found in Nebula's skull, and Star-Lord persuades Nebula into giving him the device, though she states that it telling him everything he'll want to know will also mean Star-Lord now owes her. While talking to Gamora and Drax the Destroyer, Star-Lord is told by Drax that the item is a Cypher Module - something that shouldn't exist anymore. Upon uploading it to the translator, Star-Lord uses his mask to read the ancient Kree language and is stunned to find it says "Come find me in the temple", mirroring the words of his mother in the visions. Star-Lord than tells Gamora and Drax the Destroyer that they are going back to the temple.

text: Returning to the unidentified planet with the abandoned Kree outpost, Star-Lord states that Rocket will need some space after what happened on Halfworld and that someone will need to remain behind to guard Nebula. Both Gamora and Drax the Destroyer want the opportunity to guard her - the former to try and reconnect with her sister, the latter because he believes she will start a fight he will need to quell.

text:
If Gamora is chosen to guard Nebula, Star-Lord tells Gamora that she'll be able to tell if Nebula is going to make a move.
If Drax the Destroyer is chosen to guard Nebula, he tells Star-Lord that he won't let him down.

text: On the planet's surface, Star-Lord re-enters the temple with Groot and whoever wasn't chosen to guard Nebula, using his scanner to find that Hala the Accuser was already here before them. Upon activating the switches on the statues, a platform is raised as Star-Lord translates the revealed glyphs on the wall, which exposit on how the Eternity Forge can be wielded responsibly and that "she" will remain entombed throughout the galaxy until than. Star-Lord than discovers that temple in question is at a place called Emnios, while his teammate also notes the images of the Eternity Forge displaying one life being given for every life brought back - which causes Star-Lord to realize why it failed to help Rocket; it wasn't "charged" again after it brought Star-Lord back. When Star-Lord tells whoever was left guarding Nebula to have the Milano's engines fired up for departure, he is told that Rocket is in the engine room with sounds of destruction being head.

text: In the Milano's engine room, Star-Lord finds Rocket is still mourning for Lylla and claims that she is the only thing keeping him alive, as well stating his makeshift computer - all that he has left of her - is no longer working, weeping as he states that he can't fix it this time.

text:
If Star-Lord tells Rocket to move on, he advises that Rocket let go of it, to which Rocket admits he already knows he needs to move on.
If Star-Lord tells Rocket to keep it, he tells Rocket to hold onto it as it means a lot to him, with Rocket solemnly clasping it to his body

text: As a system failure suddenly takes place across the Milano, Star-Lord leaves to deal with it as he tells Groot to help Rocket. However, Star-Lord finds the failure is actually a breech warning, as the ship is under siege by the Kree soldiers with the Revenant closing in on them. As Drax and Gamora fight them off, Nebula offers to help Star-Lord and asks he free her, stating self-preservation as a mutual goal for them to unite under.

text:
If Star-Lord agrees, he will release Nebula with a warning not to betray them, which she fulfills by helping fight off the Kree.
If Star-Lord refuses, he will leave Nebula locked up as she bitterly states he will regret his choice.

text: After dealing with the Kree in the cockpit, Star-Lord heads down to the engine room where he gets shot in the leg by Jyn-Xar, who has defeated Rocket and Groot. With the Eternity Forge in hand, Jyn-Xar states he will return it to Hala, but Star-Lord rants toward Jyn-Xar about the attack as a diversion while Rocket gets back on his feet. Depending on the advice Star-Lord gave him, Rocket will either successfully put the makeshift computer back together to help electrify Jyn-Xar, or rewire the Milano's vents in order to set Jyn-Xar on fire, with Star-Lord reclaiming the Eternity Forge from Jyn-Xar's body. Hala the Accuser than contacts Star-Lord over the radio, warning him that he can't run forever and that the Eternity Forge will be hers. Gamora tells Star-Lord that the Revenant's weapons are coming online while Rocket works to get the engines back online, barely managing to escape. Star-Lord than tells Gamora to set a course to Emnios, while dropping off their "stowaways" on the way there.

text: Closing in on Emnios, Star-Lord feels certain that his mother is on Emnios, embarking with Gamora through the opened doors into a bright light, where they see the outline of something moving.

text: More Than a Feeling[edit]

text: Following a figure into the white light from the previous episode, Star-Lord again relives a memory from his childhood. In it, the young Peter is dropped off at a music store by his mother so she can pick up a prescription from the pharmacy, having been experiencing painful headaches as of late. As the shopkeeper (Mark Barbolak) copies a mixtape for him to give him mom, Peter is harassed by the local bully Clarence (John Omohundro) who has been regularly attacking him and broke his cassette player. Clarence taunts Peter about his mother being unable to afford her medical bills and that there are rumors she has been going door-to-door begging for handouts. If left uninterrupted, Clarence says his dad is drinking buddies with Meredith's doctor and claims that she's dying, insulting her to her face when she returns to the shop.

text:
If Peter attacks Clarence, he will punch him hard enough to cause a nosebleed, causing Clarence to throw a radio at him in retaliation, though it ends up missing. Realizing he has only angered Peter further, Clarence panics and freezes up, allowing Peter to tackle him against a shelf and start pummeling him. Meredith pulls Peter off of Clarence, who laments that Peter may have broken his jaw. Disappointed and upset with Peter's actions, Meredith begins to cough and have trouble breathing as the aggravates her condition, causing the shopkeeper to call for an ambulance while Clarence runs away.
If Peter uses his words, he'll brush off Clarence's taunts and mock him for having "elephant ears", causing Clarence to rub in how Meredith kept her terminal condition secret from Peter. If Peter remains calm and insists that his mother just needs proper medicine, Clarence tells Peter to simply buy her poison so that can't waste her money trying to get better anymore. Outraged, Meredith slaps Clarence and intimidates him into fleeing, thanking Peter for not lashing out and apologizing for her poor example in striking Clarence. Peter asks Meredith if Clarence was right about her dying.

text: At the end of the flashback, Peter's mother tells him he is "so close" and tells him to find her, culminating in the adult Star-Lord waking up to find himself back on Earth in the middle of a forest. Walking through woods, he finds Gamora screaming into a field at nothing before muttering about her sister and reacting as if attacked. Confused, Star-Lord approaches Gamora only to have her start swiping at him with her sword, believing that he is Nebula. Getting pinned to the ground, Star-Lord struggles to keep Gamora's blade away from his throat and suddenly begins experiencing one of Gamora's memories just like he had with Rocket Raccoon. In it, Gamora is training with the than-unaltered Nebula in a combat arena, advising Nebula on keeping her awareness at all times when Nebula expresses frustration with being confined. The two continue dueling until finally locking blades, Nebula pleading that Gamora is hurting her.

text:
If Gamora finishes the fight, she will overpower Nebula and knock her down, but is distracted when Thanos enters the room - which Nebula takes advantage of to kick Gamora's legs out and press a blade to her neck. Thanos than compliments Nebula's use of duplicity to win and if Gamora claims Nebula cheated, Thanos will remark it Gamora's fault for leaving herself open.
If Gamora throws the fight, she eases pressure off of her sword enough for Nebula to knock her down in front of Thanos, much to Gamora's chagrin. If Gamora reveals she let Nebula win the fight, Thanos will still favor Nebula for having taken advantage of Gamora's hesitance.

text: Thanos muses that Nebula may be the greatest assassin in the galaxy and gives the sisters a mission; head to a Kree outpost on Phelion and locate General Tar-Voll, who has obtained a device that Thanos requires. He instructs Gamora to recover the device while Nebula is to kill Tar-Voll, overjoying Nebula with his acknowledgment that she is ready to go out into the galaxy. Thanos than reveals to Gamora in private that his giving Nebula the mission is because he is losing faith in Gamora's capabilities, intending for Nebula to "tighten the slack" - regardless of if she's actually capable enough yet - and that Nebula will in turn be the one who suffers if they fail. After Thanos speaks with Nebula in private, the sisters arrive on Phelion and split up to complete their goals. Infiltrating the command chamber, Gamora kills the guards and obtains the device, but Nebula is overpowered by Tar-Voll, forcing Gamora to step in and kill the General to save her. Enraged that Gamora took her kill, Nebula demands the device so that she doesn't return a failure. Gamora can either comply or refuse, but Nebula will ultimately impale Gamora with her sword to keep her failure a secret, leaving her sister for dead.

text: After the memory experience ends, Gamora reawakens and pins Star-Lord again, forcing him to slap her to snap her out of it. Realizing he saw her memories, Gamora reveals the betrayal is the main reason for her bitterness with Nebula and that her sister resented her acts of protection, seeing it as pity and a lack of trust. However, Gamora states she also blames herself for not being more honest with Nebula about her doubts and that she still wants to repair their relationship, despite fearing that Nebula will never stop resenting her. Returning focus onto what the Temple is trying to show them, Star-Lord and Gamora hear music that the former recognizes as one of his mother's favorites, drawing them to an old chapel in the middle of the forest. Gamora warns Star-Lord to be careful as the Temple is using their memories against them, entering the chapel to find it a recreation of Meredith's funeral, albeit devoid of anybody else. As they approach the podium, the music intensifies and distorts until going quiet when Star-Lord reaches the casket and opens it, releasing a bright light that disperses the memory world and reveals the Temple on Emnios. Finding a large container in place of his mother's casket, Star-Lord and Gamora watch the object open to reveal the body of a female figure, which tumbles onto the floor.

text: Discovering the figure to be a humanoid girl with a pair of antennae, the woman introduces herself as Mantis (Sumalee Montano) and calls Peter by name, claiming they have met before - than asks to borrow Peter's gun. Star-Lord can oblige her or refuse, though either way Mantis will force her prison container over the edge of the platform and destroy it, gladdened to finally be free of her "tomb". Proclaiming Peter to be "the Celestial One", Mantis reveals she was the source of Peter's visions through the Eternity Forge, calling for him to come find her - albeit unconsciously, with the message using Peter's most vivid memories, and by extension Meredith's form, on reflex to communicate it. Apologizing for her actions, Mantis holds Star-Lord's hands and is able read his responses before he even speaks, revealing she is an empath that can read others' emotions or transmit her own to them, explaining her duty is to help "the Celestial One" decide the fate of the Eternity Forge. Returning Mantis to the Milano, Star-Lord and Gamora introduce her to the rest of the Guardians by way of showcasing her abilities on either Drax the Destroyer, Rocket Raccoon or Groot. Star-Lord explains Mantis was the one calling to them through their memories, to which Drax questions how Mantis is connected to the Eternity Forge, despite Rocket's protests against a lengthy narration.

text: If allowed to speak of her past, Mantis explains that the Eternity Forge was brought into existence eons ago as a way to balance the Universe's flow of life-energy, by allowing control over the cycles of life and death. Mantis herself was charged with serving as both its guardian and a guide for it's wielder to ensure only someone worthy could use it - but when none came, the Kree separated Mantis from the Forge and locked them away separately, so that it's power couldn't be abused. Mantis than explains that there is a legend of "the Celestial One" - a chosen hero with the wisdom and insight to wield the Eternity Forge and decide both its use and it's ultimate fate - and that Star-Lord is the one the legend speaks of. Rocket is skeptical of the Legend since the Forge wasn't able to bring Lylla back, to which Mantis explains the Eternity Forge is only operating in a limited capacity - unless it is restored to full power, it can only resurrect intact and undamaged corpses, which in turn explains why Hala was preserving Kree bodies. However, Mantis reveals that as the Celestial One, Peter can restore the Forge to its full power if he returns it to the Sacred Shrine, which would allow it to resurrect any deceased being from any point, though at the cost of one life for another - or he can destroy it to keep its power forever out of evil hands. Rocket and Drax want to use it to bring back their loved ones, but Gamora and Groot wish it to be destroyed so that it's power can't be abused, by Hala or anyone else.

text: Star-Lord asks if Mantis can take them to the Shrine, to which she states she may be able to sense it's location with his help. However, the unrest and division among the crew makes it too difficult for Mantis to try, asking Star-Lord to speak with them first and find it’s source. Star-Lord finds Groot caring for a potted seedling and Rocket drinking his sorrows away, while Drax the Destroyer feels pensive over hope he'll get his family back and anxiety over Mantis' peering into people's feelings - as well as sympathy for the kind of pain that insight causes. Finally, Star-Lord discovers the primary source of unrest is from Gamora and Nebula, the former voicing frustration and uncertainty over failing to reach her sister. Star-Lord can advise Gamora to either give up on Nebula or keep trying to reach her, before going to speak with Nebula himself. Expressing bitterness at Gamora's attempts to speak with her, Nebula claims her sister doesn't know the full truth behind why she betrayed her, to which Star-Lord suggests she show him via Mantis' empathic abilities. Agreeing, Nebula shows Star-Lord her memories of the sisters' last mission, revealing that she hadn't been trying to kill Gamora; Thanos had been listening in as he believed that Gamora was untrustworthy. When Gamora disobeyed him and killed Tar-Voll, Thanos ordered Nebula to kill Gamora lest he do so himself, albeit slowly and painfully, with Nebula complying in order to save Gamora from Thanos' wrath. Gamora than walks in on Star-Lord viewing Nebula's memories and interrupts, causing another argument between them over each-other's trustworthiness despite them both wanting to reconnect.

text:
If Star-Lord tells Nebula to leave, she will bitterly depart and end up joining Hala the Accuser in order to gain protection from the Nova Corps. She than fights Gamora in the episode's climax, taunting her for never listening to her while Gamora vows to keep defeating her, though the fight ultimately ends with Nebula helping subdue Gamora.
If Star-Lord tells Nebula to stay, she and Gamora finally start to reconcile and Nebula accompanies the Guardians, leaving Gamora hopeful they can regain each-other's trust. Nebula and Gamora fight side-by-side in the episode's climax, expressing happiness at working together again, though Nebula ends up getting injured protecting Gamora.

text: With the crew's feelings now sorted out, Mantis is able to locate the Sacred Shrine and the crew readies to leave. Gamora talks with Star-Lord about the outcome of taking to Nebula, Rocket apologizes for his drunken rant at Peter and Mantis listens to music on Peter's cassette player, voicing anxiety on how much the team is weighed down by their pasts rather than living in the present. Playing some music to help ease tension, Star-Lord helps Mantis acclimatize to the Guardian's chaotic life on the Milano as they travel to the Shrine, which is located in a subterranean cavern on Drobino. Entering the Shrine, Mantis directs Star-Lord to place the Eternity Forge on the central pedestal and energize the temple, though damage to the statues forces them to manually re-adjust the lenses meant to focus power to the platform. Upon focusing the beams of light on the Eternity Forge, Star-Lord is given the choice of whether or not to fully empower it or destroy it, but Hala the Accuser enters immediately afterword with a group of Kree soldiers to try and claim it for herself, though Rocket disarms her of the remote-gauntlet for her lance.

text:
If Star-Lord decides to destroy the Eternity Forge, Drax the Destroyer and Rocket Raccoon feel hurt and betrayed at losing the chance to have their loved ones back, verbally lashing out at Gamora and Groot when they approve of the choice. When Hala enters, the Guardians fight her forces to a standstill but Hala manages to reach the broken Eternity Forge. She than attempts to resurrect her son Bal-Dinn, but his body disintegrates moments after materializing and the stricken Eternity Forge explodes. However, Hala survives the blast, badly burned but infused with the Forge's power, swearing revenge on Peter for costing her the chance to bring back her son and army.
If Star-Lord decides to empower the Eternity Forge, Gamora and Groot will respectively express anger and disappointment at personal attachment superseding the risk, with Drax the Destroyer and Rocket Raccoon criticizing the two for being afraid. When Hala enters, the Guardians fight her forces to a standstill but Hala manages to reach the empowered Eternity Forge. She than uses it to successfully resurrect her son Bal-Dinn (Johnny Yong Bosch), embracing him upon affirming he is alive. Claiming the Eternity Forge for herself, Hala uses it to revive the rest of her soldiers within the Shrine, intent on repeating the process for the Kree's army.

text: Who Needs You[edit]

text: This section needs expansion. You can help by adding to it. (October 2017)

text: Episodes[edit]

text: The game was separated into five episodes for release on mobile devices, personal computers, and PlayStation 4 and Xbox One consoles.[9] The version of the series for the Nintendo Switch was announced in August 2017, though its release date is not yet known.[10]

text:
No.
Title
Directed by
Written by
Original release date

1
"Tangled Up in Blue"
Jonathan Stauder
Zack Keller, Nicole Martinez & Timothy Williams
April 18, 2017 (2017-04-18)[1]

The Guardians help the Nova Corps intercept Thanos as he steals an artifact from an ancient Kree tomb called the Eternity Forge. Star-Lord uses Rocket's atomic gun to kill the Mad Titan, and after a night of celebration at a bar on Knowhere rack up a hefty tab. When getting the money to pay the tab, Hala the Accuser attacks the team and takes the Eternity Forge from Star-Lord's possession to resurrect the extinct Kree Empire. Peter pursues her with (either Drax or Gamora) to her ship. She mortally wounds Star-Lord, who barely escapes her with the Forge. In death, Peter sees his mother who, by way of the Eternity Forge, restores her son to life.

2
"Under Pressure"
Jason Latino
Nicole Martinez, Jessica Krause & Timothy Williams
June 6, 2017 (2017-06-06)[2]

When the Guardians stop on Rajak for repairs, Star-Lord visits his adoptive father Yondu to learn how the Eternity Forge and his mother Meredith are connected. Experiencing another vision, Peter is shown Kree glyphs that Gamora thinks Nebula can translate, but Rocket wishes to detour to Halfworld to see if the Eternity Forge can bring back his lost friend Lylla. After persuading Nebula to help them, the Guardians return to the artifact's temple and are directed to Emnios, but are attacked by Hala's Kree soldiers. Barely escaping, the Guardians arrive on Emnios, where Peter believes he'll find his mother.

3
"More than a Feeling"
Mark Droste
Meghan Thornton, Zack Keller and Jessica Krause
August 22, 2017 (2017-08-22)[3]

Entering the Temple on Emnios, Peter experiences another memory of his childhood while Gamora relives Nebula betraying her. Finding a casket within the Temple, they open it and release an alien named Mantis - the Eternity Forge's guardian and the one who called out to Star-Lord using his mother's image, believing he is "The Celestial One" destined to determine the Forge's fate. Guided by Mantis to the Kree's Sacred Shrine on Drobino, Star-Lord must decide whether to empower or destroy the Eternity Forge - a choice the rest of the Guardians are hotly divided on - before Hala arrives to try and claim it for herself.

4
"Who Needs You"
TBA
TBA
October 10, 2017 (2017-10-10)

5
"Don't Stop Believin'"
TBA
TBA
November 7, 2017 (2017-11-07)

text: Reception[edit]

text:
Aggregate review scores

Game
Metacritic

Episode 1: Tangled Up in Blue
(PC) 70[11]
(PS4) 72[12]
(XONE) 74[13]

Episode 2: Under Pressure
(PC) 72[14]
(PS4) 70[15]
(XONE) 78[16]

Episode 3: More Than A Feeling
(PC) 72[17]
(PS4) 68[18]
(XONE) 70[19]

text: Guardians of the Galaxy: The Telltale Series received favorable reviews from critics earning praise for its story, voice acting, action sequences, and portrayal of the titular characters, although its humor, animation, and technical issues have been criticized.

text: Episode 1: Tangled Up in Blue[edit]

text: Aggregating review website Metacritic gave the Microsoft Windows version 70/100 based on 21 reviews,[11] the PlayStation 4 version 72/100 based on 29 reviews[12] and the Xbox One version 74/100 based on 12 reviews.[13]

text: Episode 2: Under Pressure[edit]

text: Aggregating review website Metacritic gave the Microsoft Windows version 72/100 based on 12 reviews,[14] the PlayStation 4 version 70/100 based on 9 reviews[15] and the Xbox One version 78/100 based on 6 reviews.[16]

text: Episode 3: More Than A Feeling[edit]

text: Aggregating review website Metacritic gave the Microsoft Windows version 72/100 based on 10 reviews,[17] the PlayStation 4 version 68/100 based on 6 reviews[18] and the Xbox One version 70/100 based on 8 reviews.[19]


document_title: List of first black Major League Baseball players

question_text: who was the first black player in the major league baseball

root

text: Overall[edit]

text:
Player

Team

League

Date

Jackie Robinson †

Brooklyn Dodgers

NL

April 15, 1947

Larry Doby †

Cleveland Indians

AL

July 5, 1947

Hank Thompson

St. Louis Browns

AL

July 17, 1947

Willard Brown †

St. Louis Browns

AL

July 19, 1947

Dan Bankhead

Brooklyn Dodgers

NL

August 26, 1947

Roy Campanella †

Brooklyn Dodgers

NL

April 20, 1948

Satchel Paige †

Cleveland Indians

AL

July 9, 1948

Minnie Miñoso

Cleveland Indians

AL

April 19, 1949

Don Newcombe

Brooklyn Dodgers

NL

May 20, 1949

Monte Irvin †

New York Giants

NL

July 8, 1949

Luke Easter

Cleveland Indians

AL

August 11, 1949

Sam Jethroe

Boston Braves

NL

April 18, 1950

Luis Márquez

Boston Braves

NL

April 18, 1951

Ray Noble

New York Giants

NL

Artie Wilson

New York Giants

NL

Harry Simpson

Cleveland Indians

AL

April 21, 1951

Willie Mays †

New York Giants

NL

May 25, 1951

Sam Hairston

Chicago White Sox

AL

July 21, 1951

Bob Boyd

Chicago White Sox

AL

September 8, 1951

Sam Jones

Cleveland Indians

AL

September 22, 1951

tag: table

text: Johnny Wright was the second black player signed to a contract by the Dodgers, and was on the roster of the 1946 Montreal Royals at the same time as Jackie Robinson.[1]

tag: p

text: By team[edit]

text:
Teams are listed by franchise; i.e., teams that relocated to a new city after already breaking the color line are not listed a second time.
Expansion teams that joined the National and American Leagues after 1961 have been integrated from their first game and are not listed.

tag: ul

text:
Player

Team

League

Date[2]

Jackie Robinson †

Brooklyn Dodgers

NL

April 15, 1947

Larry Doby †

Cleveland Indians

AL

July 5, 1947

Hank Thompson

St. Louis Browns

AL

July 17, 1947

Hank Thompson

New York Giants

NL

July 8, 1949‡

Monte Irvin †

Sam Jethroe

Boston Braves

NL

April 18, 1950

Minnie Miñoso

Chicago White Sox

AL

May 1, 1951

Bob Trice

Philadelphia Athletics

AL

September 13, 1953

Ernie Banks †

Chicago Cubs

NL

September 17, 1953

Curt Roberts*

Pittsburgh Pirates

NL

April 13, 1954

Tom Alston

St. Louis Cardinals

NL

April 13, 1954

Nino Escalera

Cincinnati Reds

NL

April 17, 1954

Chuck Harmon[3]

Carlos Paula

Washington Senators

AL

September 6, 1954

Elston Howard

New York Yankees

AL

April 14, 1955

John Kennedy

Philadelphia Phillies

NL

April 22, 1957

Ozzie Virgil, Sr.[4]

Detroit Tigers

AL

June 6, 1958

Pumpsie Green

Boston Red Sox

AL

July 21, 1959

text:
* Major League Baseball recognizes Curt Roberts as the Pirates' first black player, however Carlos Bernier of Puerto Rico, also a black man, debuted on April 22, 1953.[5]
‡ Thompson and Irvin broke in with the Giants during the same game on July 8, 1949. Hank was the starting third baseman, and Monte pinch hit in the eighth.[1]


document_title: Chickenpox

question_text: where does chicken pox live in the body

question_tokens: where does chicken pox live in the body

text: Chickenpox

text: Signs and symptoms[edit]

text: The early (prodromal) symptoms in adolescents and adults are nausea, loss of appetite, aching muscles, and headache. This is followed by the characteristic rash or oral sores, malaise, and a low-grade fever that signal the presence of the disease. Oral manifestations of the disease (enanthem) not uncommonly may precede the external rash (exanthem). In children the illness is not usually preceded by prodromal symptoms, and the first sign is the rash or the spots in the oral cavity. The rash begins as small red dots on the face, scalp, torso, upper arms and legs; progressing over 10–12 hours to small bumps, blisters and pustules; followed by umbilication and the formation of scabs.[15][16]

text: At the blister stage, intense itching is usually present. Blisters may also occur on the palms, soles, and genital area. Commonly, visible evidence of the disease develops in the oral cavity and tonsil areas in the form of small ulcers which can be painful or itchy or both; this enanthem (internal rash) can precede the exanthem (external rash) by 1 to 3 days or can be concurrent. These symptoms of chickenpox appear 10 to 21 days after exposure to a contagious person. Adults may have a more widespread rash and longer fever, and they are more likely to experience complications, such as varicella pneumonia.[15]

text: Because watery nasal discharge containing live virus usually precedes both exanthem (external rash) and enanthem (oral ulcers) by 1 to 2 days, the infected person actually becomes contagious one to two days before recognition of the disease. Contagiousness persists until all vesicular lesions have become dry crusts (scabs), which usually entails four or five days, by which time nasal shedding of live virus ceases.

text: The condition usually resolves by itself within a couple of weeks.[17] The rash may, however, last for up to one month.[medical citation needed] Chickenpox is contagious starting from one to two days before the appearance of the rash and lasts until the lesions have crusted.[18]

text: Chickenpox is rarely fatal, although it is generally more severe in adult men than in women or children. Non-immune pregnant women and those with a suppressed immune system are at highest risk of serious complications. Arterial ischemic stroke (AIS) associated with chickenpox in the previous year accounts for nearly one third of childhood AIS.[19] The most common late complication of chickenpox is shingles (herpes zoster), caused by reactivation of the varicella zoster virus decades after the initial, often childhood, chickenpox infection.

text:
The back of a 30-year-old male after five days of the rash

A 3-year-old girl with a chickenpox rash on her torso

Lower leg of a child with chickenpox

A child with chickenpox

A child with chickenpox on her face.

text: Pregnancy and neonates[edit]

text: During pregnancy the dangers to the fetus associated with a primary VZV infection are greater in the first six months. In the third trimester, the mother is more likely to have severe symptoms.[20] For pregnant women, antibodies produced as a result of immunization or previous infection are transferred via the placenta to the fetus.[21] Varicella infection in pregnant women could lead to spread via the placenta and infection of the fetus. If infection occurs during the first 28 weeks of gestation, this can lead to fetal varicella syndrome (also known as congenital varicella syndrome).[22] Effects on the fetus can range in severity from underdeveloped toes and fingers to severe anal and bladder malformation. Possible problems include:

text:
Damage to brain: encephalitis,[23] microcephaly, hydrocephaly,[24] aplasia of brain
Damage to the eye: optic stalk, optic cup, and lens vesicles, microphthalmia, cataracts, chorioretinitis, optic atrophy
Other neurological disorder: damage to cervical and lumbosacral spinal cord, motor/sensory deficits, absent deep tendon reflexes, anisocoria/Horner's syndrome
Damage to body: hypoplasia of upper/lower extremities, anal and bladder sphincter dysfunction
Skin disorders: (cicatricial) skin lesions, hypopigmentation

text: Infection late in gestation or immediately following birth is referred to as "neonatal varicella".[25] Maternal infection is associated with premature delivery. The risk of the baby developing the disease is greatest following exposure to infection in the period 7 days before delivery and up to 8 days following the birth. The baby may also be exposed to the virus via infectious siblings or other contacts, but this is of less concern if the mother is immune. Newborns who develop symptoms are at a high risk of pneumonia and other serious complications of the disease.[26]

text: Diagnosis[edit]

text: The diagnosis of chickenpox is primarily based on the signs and symptoms, with typical early symptoms followed by a characteristic rash. Confirmation of the diagnosis is by examination of the fluid within the vesicles of the rash, or by testing blood for evidence of an acute immunologic response.

text: Vesicular fluid can be examined with a Tzanck smear, or by testing for direct fluorescent antibody. The fluid can also be "cultured", whereby attempts are made to grow the virus from a fluid sample. Blood tests can be used to identify a response to acute infection (IgM) or previous infection and subsequent immunity (IgG).[27]

text: Prenatal diagnosis of fetal varicella infection can be performed using ultrasound, though a delay of 5 weeks following primary maternal infection is advised. A PCR (DNA) test of the mother's amniotic fluid can also be performed, though the risk of spontaneous abortion due to the amniocentesis procedure is higher than the risk of the baby's developing fetal varicella syndrome.[26]

text: Pathophysiology[edit]

text: Exposure to VZV in a healthy child initiates the production of host immunoglobulin G (IgG), immunoglobulin M (IgM), and immunoglobulin A (IgA) antibodies; IgG antibodies persist for life and confer immunity. Cell-mediated immune responses are also important in limiting the scope and the duration of primary varicella infection. After primary infection, VZV is hypothesized to spread from mucosal and epidermal lesions to local sensory nerves. VZV then remains latent in the dorsal ganglion cells of the sensory nerves. Reactivation of VZV results in the clinically distinct syndrome of herpes zoster (i.e., shingles), postherpetic neuralgia,[28] and sometimes Ramsay Hunt syndrome type II.[29] Varicella zoster can affect the arteries in the neck and head, producing stroke, either during childhood, or after a latency period of many years.[30]

text: Shingles[edit]

text: After a chickenpox infection, the virus remains dormant in the body's nerve tissues. The immune system keeps the virus at bay, but later in life, usually in an adult, it can be reactivated and cause a different form of the viral infection called shingles (also known as herpes zoster).[31] The United States Advisory Committee on Immunization Practices (ACIP) suggests that every adult over the age of 60 years get the herpes zoster vaccine.[32]

text: Shingles affects one in five adults infected with chickenpox as children, especially those who are immune-suppressed, particularly from cancer, HIV, or other conditions. Stress can bring on shingles as well, although scientists are still researching the connection.[33] Shingles are most commonly found in adults over the age of 60 who were diagnosed with chickenpox when they were under the age of 1.[34]

text: Prevention[edit]

text: Hygiene measures[edit]

text: The spread of chickenpox can be prevented by isolating affected individuals. Contagion is by exposure to respiratory droplets, or direct contact with lesions, within a period lasting from three days before the onset of the rash, to four days after the onset of the rash.[35] The chickenpox virus is susceptible to disinfectants, notably chlorine bleach (i.e., sodium hypochlorite). Like all enveloped viruses, it is sensitive to desiccation, heat and detergents.

text: Vaccine[edit]

text: The varicella vaccine is recommended in many countries.[10] Some countries require the varicella vaccination or an exemption before entering elementary school. A second dose is recommended five years after the initial immunization.[36] A vaccinated person is likely to have a milder case of chickenpox if they become infected.[37] Immunization within three days following household contact reduces infection rates and severity in children.[11]

text: It is part of the routine immunization schedule in the US.[38] Some European countries include it as part of universal vaccinations in children,[39] but not all countries provide the vaccine due to its cost.[10] In the UK as of 2014, the vaccine is only recommended in people who are particularly vulnerable to chickenpox.[40] In populations that have not been immunized or if immunity is questionable, a clinician may order an Enzyme immunoassay. An immunoassay measures the levels of antibodies against the virus that give immunity to a person. If the levels of antibodies are low (low titer) or questionable, reimmunization may be done.[41]

text: Treatment[edit]

text: Treatment mainly consists of easing the symptoms. As a protective measure, people are usually required to stay at home while they are infectious to avoid spreading the disease to others. Cutting the nails short or wearing gloves may prevent scratching and minimize the risk of secondary infections.

text: Although there have been no formal clinical studies evaluating the effectiveness of topical application of calamine lotion (a topical barrier preparation containing zinc oxide, and one of the most commonly used interventions), it has an excellent safety profile.[42] It is important to maintain good hygiene and daily cleaning of skin with warm water to avoid secondary bacterial infection.[43] Scratching may also increase the risk of secondary infection.[44]

text: Paracetamol (acetaminophen) but not aspirin may be used to reduce fever. Aspirin use by someone with chickenpox may cause the serious, sometimes fatal disease of the liver and brain, Reye syndrome. People at risk of developing severe complications who have had significant exposure to the virus may be given intra-muscular varicella zoster immune globulin (VZIG), a preparation containing high titres of antibodies to varicella zoster virus, to ward off the disease.[45][46]

text: Antivirals are sometimes used.[47][48]

text: Children[edit]

text: If aciclovir by mouth is started within 24 hours of rash onset, it decreases symptoms by one day but has no effect on complication rates.[49][50] Use of acyclovir therefore is not currently recommended for individuals with normal immune function. Children younger than 12 years old and older than one month are not meant to receive antiviral drugs unless they have another medical condition which puts them at risk of developing complications.[51]

text: Treatment of chickenpox in children is aimed at symptoms while the immune system deals with the virus. With children younger than 12 years, cutting nails and keeping them clean is an important part of treatment as they are more likely to scratch their blisters more deeply than adults.[52]

text: Aspirin is highly contraindicated in children younger than 16 years, as it has been related to Reye syndrome.[53]

text: Adults[edit]

text: Infection in otherwise healthy adults tends to be more severe.[54] Treatment with antiviral drugs (e.g. acyclovir or valacyclovir) is generally advised, as long as it is started within 24–48 hours from rash onset.[51] Remedies to ease the symptoms of chickenpox in adults are basically the same as those used for children. Adults are more often prescribed antiviral medication, as it is effective in reducing the severity of the condition and the likelihood of developing complications. Antiviral medicines do not kill the virus but stop it from multiplying. Adults are advised to increase water intake to reduce dehydration and to relieve headaches. Painkillers such as paracetamol (acetaminophen) are recommended, as they are effective in relieving itching and other symptoms such as fever or pains. Antihistamines relieve itching and may be used in cases where the itching prevents sleep, because they also act as a sedative. As with children, antiviral medication is considered more useful for those adults who are more prone to develop complications. These include pregnant women or people who have a weakened immune system.[55]

text: Sorivudine, a nucleoside analogue, has been reported to be effective in the treatment of primary varicella in healthy adults (case reports only), but large-scale clinical trials are still needed to demonstrate its efficacy.[56]

text: After recovering from chickenpox, it is recommended by doctors that adults take one injection of VZV immune globulin and one injection of varicella vaccine or herpes zoster vaccine.[citation needed]

text: Prognosis[edit]

text: The duration of the visible blistering caused by varicella zoster virus varies in children usually from 4 to 7 days, and the appearance of new blisters begins to subside after the fifth day. Chickenpox infection is milder in young children, and symptomatic treatment, with sodium bicarbonate baths or antihistamine medication may ease itching. It is recommended to keep new infants from birth up to age 6 months away from an infected person for 10 to 21 days because their immune systems are not developed enough to handle the stress it can bring on.[57] Paracetamol (acetaminophen) is widely used to reduce fever. Aspirin, or products containing aspirin, should not be given to children with chickenpox, as it can cause Reye's Syndrome.[58]

text: In adults, the disease is more severe,[59] though the incidence is much less common. Infection in adults is associated with greater morbidity and mortality due to pneumonia (either direct viral pneumonia or secondary bacterial pneumonia),[60] bronchitis (either viral bronchitis or secondary bacterial bronchitis),[60] hepatitis,[61] and encephalitis.[62] In particular, up to 10% of pregnant women with chickenpox develop pneumonia, the severity of which increases with onset later in gestation. In England and Wales, 75% of deaths due to chickenpox are in adults.[26] Inflammation of the brain, or encephalitis, can occur in immunocompromised individuals, although the risk is higher with herpes zoster.[63] Necrotizing fasciitis is also a rare complication.[64]

text: Varicella can be lethal to adults with impaired immunity. The number of people in this high-risk group has increased, due to the HIV epidemic and the increased use of immunosuppressive therapies.[65] Varicella is a particular problem in hospitals, when there are patients with immune systems weakened by drugs (e.g., high-dose steroids) or HIV.[66]

text: Secondary bacterial infection of skin lesions, manifesting as impetigo, cellulitis, and erysipelas, is the most common complication in healthy children. Disseminated primary varicella infection usually seen in the immunocompromised may have high morbidity. Ninety percent of cases of varicella pneumonia occur in the adult population. Rarer complications of disseminated chickenpox include myocarditis, hepatitis, and glomerulonephritis.[67]

text: Hemorrhagic complications are more common in the immunocompromised or immunosuppressed populations, although healthy children and adults have been affected. Five major clinical syndromes have been described: febrile purpura, malignant chickenpox with purpura, postinfectious purpura, purpura fulminans, and anaphylactoid purpura. These syndromes have variable courses, with febrile purpura being the most benign of the syndromes and having an uncomplicated outcome. In contrast, malignant chickenpox with purpura is a grave clinical condition that has a mortality rate of greater than 70%. The cause of these hemorrhagic chickenpox syndromes is not known.[67]

text: Epidemiology[edit]

text: Primary varicella occurs in all countries worldwide. In 2013 the disease resulted in 7,000 deaths – down from 8,900 in 1990.[13]

text: In temperate countries, chickenpox is primarily a disease of children, with most cases occurring during the winter and spring, most likely due to school contact. It is one of the classic diseases of childhood, with the highest prevalence in the 4–10-year-old age group. Like rubella, it is uncommon in preschool children. Varicella is highly communicable, with an infection rate of 90% in close contacts. In temperate countries, most people become infected before adulthood, and 10% of young adults remain susceptible.

text: In the tropics, chickenpox often occurs in older people and may cause more serious disease.[68] In adults, the pock marks are darker and the scars more prominent than in children.[69]

text: In the United States, the Centers for Disease Control and Prevention (CDC) does not require state health departments to report infections of chickenpox, and only 31 states currently volunteer this information.[70] However, in a 2013 study conducted by the social media disease surveillance tool called Sickweather, anecdotal reports of chickenpox infections on Facebook and Twitter were used to measure and rank states with the most infections per capita, with Maryland, Tennessee and Illinois in the top three.[71]

text: Etymology[edit]

text: Why the term was used is not clear but it may be due to it being a relatively mild disease.[14] It has been said to be derived from chickpeas, based on resemblance of the vesicles to chickpeas,[14][72][73] or to come from the rash resembling chicken pecks.[73] Other suggestions include the designation chicken for a child (i.e., literally 'child pox'), a corruption of itching-pox,[72][74] or the idea that the disease may have originated in chickens.[75] Samuel Johnson explained the designation as "from its being of no very great danger".[76]

text: Society and culture[edit]

text: Because chickenpox is usually more severe in adults than it is in children, some parents deliberately expose their children to the virus, sometimes by taking them to "chickenpox parties". Doctors counter that children are safer getting the vaccine, which is a weakened form of the virus, rather than getting the disease, which can be fatal.[77]

text: Other animals[edit]

text: Humans are the only known species that the disease affects naturally.[7] However, chickenpox has been caused in other animals, such as primates, including chimpanzees[78] and gorillas.[79]