document_title: Cell cycle

question_text: in which cell life cycle phase is a cell highly active and growing

text: Cell cycle

text: Phases[edit]

text: The cell cycle consists of four distinct phases: G1 phase, S phase (synthesis), G2 phase (collectively known as interphase) and M phase (mitosis or meiosis). M phase is itself composed of two tightly coupled processes: karyokinesis, in which the cell's chromosomes are divided, and cytokinesis, in which the cell's cytoplasm divides forming two daughter cells. Activation of each phase is dependent on the proper progression and completion of the previous one. Cells that have temporarily or reversibly stopped dividing are said to have entered a state of quiescence called G0 phase.

text:
State

Phase

Abbreviation

Description

Resting

Gap 0

G0

A phase where the cell has left the cycle and has stopped dividing.

Interphase

Gap 1

G1

Cells increase in size in Gap 1. The G1 checkpoint control mechanism ensures that everything is ready for DNA synthesis.

Synthesis

S

DNA replication occurs during this phase.

Gap 2

G2

During the gap between DNA synthesis and mitosis, the cell will continue to grow. The G2 checkpoint control mechanism ensures that everything is ready to enter the M (mitosis) phase and divide.

Cell division

Mitosis

M

Cell growth stops at this stage and cellular energy is focused on the orderly division into two daughter cells. A checkpoint in the middle of mitosis (Metaphase Checkpoint) ensures that the cell is ready to complete cell division.

text: After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.

text: G0 phase (quiescence)[edit]

text: G0 is a resting phase where the cell has left the cycle and has stopped dividing.  The cell cycle starts with this phase.  The word "post-mitotic" is sometimes used to refer to both quiescent and senescent cells. Non-proliferative (non-dividing) cells in multicellular eukaryotes generally enter the quiescent G0 state from G1 and may remain quiescent for long periods of time, possibly indefinitely (as is often the case for neurons). This is very common for cells that are fully differentiated. Cellular senescence occurs in response to DNA damage and external stress and usually constitutes an arrest in G1. Some cells enter the G0 phase semi-permanently and are considered post-mitotic, e.g., some liver, kidney, and stomach cells. Many cells do not enter G0 and continue to divide throughout an organism's life, e.g., epithelial cells.

text: Cellular senescence is also a state that occurs in response to DNA damage or degradation that would make a cell's progeny nonviable; it is often a biochemical alternative to the self-destruction of such a damaged cell by apoptosis.

text: Interphase (intermitosis)[edit]

text: Before a cell can enter cell division, it needs to take in nutrients. All of the preparations are done during interphase. Interphase is a series of changes that takes place in a newly formed cell and its nucleus, before it becomes capable of division again. It is also called preparatory phase or intermitosis. Previously it was called resting stage because there is no apparent activity related to cell division.Typically interphase lasts for at least 91% of the total time required for the cell cycle.

text: Interphase proceeds in three stages, G1, S, and G2, followed by the cycle of mitosis and cytokinesis. The cell's nuclear DNA contents are duplicated during S phase but may continue till G2 in case of heterochromatin.

text: G1 phase (First growth phase or Post mitotic gap phase)[edit]

text:
The first phase within interphase, from the end of the previous M phase until the beginning of DNA synthesis, is called G1 (G indicating gap). It is also called the growth phase. During this phase, the biosynthetic activities of the cell, which are considerably slowed down during M phase, resume at a high rate. The duration of G1 is highly variable, even among different cells of the same species.[3] In this phase, the cell increases its supply of proteins, increases the number of organelles (such as mitochondria, ribosomes), and grows in size. In G1 phase, a cell has three options.
(1) To continue cell cycle and enter S phase
(2) Stop cell cycle and enter G0 phase for undergoing differentiation.
(3) Get arrested in G1 phase hence it may enter G0 phase or re-enter cell cycle.
The deciding factor is availability of nutrients and storage of energy rich compounds at the deciding point called check point (Restriction point). This check point is called the restriction point or START and is regulated by G1/S cyclins, which cause transition from G1 to S phase. Passage through the  G1 check point commits the cell to division.

text: S phase (DNA replication)[edit]

text: The ensuing S phase starts when DNA synthesis commences; when it is complete, all of the chromosomes have been replicated, i.e., each chromosome has two (sister) chromatids. Thus, during this phase, the amount of DNA in the cell has effectively doubled, though the ploidy of the cell remains the same. Rates of RNA transcription and protein synthesis are very low during this phase. An exception to this is histone production, most of which occurs during the S phase.[4][5][6]

text: G2 phase (growth)[edit]

text:
G2 phase occurs after DNA replication and is a period of protein synthesis and rapid cell growth to prepare the cell for mitosis.
During this phase microtubules begin to reorganize to form a spindle.

text: Mitotic phase (chromosome separation)[edit]

text: The relatively brief M phase consists of nuclear division (karyokinesis). It is a relatively short period of the cell cycle. M phase is complex and highly regulated. The sequence of events is divided into phases, corresponding to the completion of one set of activities and the start of the next. These phases are sequentially known as:

text:
prophase,
metaphase,
anaphase,
telophase

text: Mitosis is the process by which a eukaryotic cell separates the chromosomes in its cell nucleus into two identical sets in two nuclei.[7] During the process of mitosis the pairs of chromosomes condense and attach to fibers that pull the sister chromatids to opposite sides of the cell.[8]

text: Mitosis occurs exclusively in eukaryotic cells, but occurs in different ways in different species. For example, animals undergo an "open" mitosis, where the nuclear envelope breaks down before the chromosomes separate, while fungi such as Aspergillus nidulans and Saccharomyces cerevisiae (yeast) undergo a "closed" mitosis, where chromosomes divide within an intact cell nucleus.[9] Prokaryotic cells, which lack a nucleus, divide by a process called binary fission.

text: Cytokinesis phase (separation of all cell components)[edit]

text: Mitosis is immediately followed by cytokinesis, which divides the nuclei, cytoplasm, organelles and cell membrane into two cells containing roughly equal shares of these cellular components. Mitosis and cytokinesis together define  the division of the mother cell into two daughter cells, genetically identical to each other and to their parent cell. This accounts for approximately 10% of the cell cycle.

text: Because cytokinesis usually occurs in conjunction with mitosis, "mitosis" is often used interchangeably with "M phase". However, there are many cells where mitosis and cytokinesis occur separately, forming single cells with multiple nuclei in a process called endoreplication. This occurs most notably among the fungi and slime moulds, but is found in various groups. Even in animals, cytokinesis and mitosis may occur independently, for instance during certain stages of fruit fly embryonic development.[10] Errors in mitosis can either kill a cell through apoptosis or cause mutations that may lead to cancer.

text: The process of mitosis is complex and highly regulated. The sequence of events is divided into phases, corresponding to the completion of one set of activities and the start of the next. These stages are prophase, prometaphase, metaphase, anaphase and telophase. During the process of mitosis the pairs of chromosomes condense and attach to fibers that pull the sister chromatids to opposite sides of the cell. The cell then divides in cytokinesis, to produce two identical daughter cells.[8]

text: Regulation of eukaryotic cell cycle[edit]

text: Regulation of the cell cycle involves processes crucial to the survival of a cell, including the detection and repair of genetic damage as well as the prevention of uncontrolled cell division. The molecular events that control the cell cycle are ordered and directional; that is, each process occurs in a sequential fashion and it is impossible to "reverse" the cycle.

text: Role of cyclins and CDKs[edit]

text:
Nobel LaureatePaul Nurse

Nobel LaureateTim Hunt

text: Two key classes of regulatory molecules, cyclins and cyclin-dependent kinases (CDKs), determine a cell's progress through the cell cycle.[11] Leland H. Hartwell, R. Timothy Hunt, and Paul M. Nurse won the 2001 Nobel Prize in Physiology or Medicine for their discovery of these central molecules.[12] Many of the genes encoding cyclins and CDKs are conserved among all eukaryotes, but in general more complex organisms have more elaborate cell cycle control systems that incorporate more individual components. Many of the relevant genes were first identified by studying yeast, especially Saccharomyces cerevisiae;[13] genetic nomenclature in yeast dubs many of these genes cdc (for "cell division cycle") followed by an identifying number, e.g. cdc25 or cdc20.

text: Cyclins form the regulatory subunits and CDKs the catalytic subunits of an activated heterodimer; cyclins have no catalytic activity and CDKs are inactive in the absence of a partner cyclin. When activated by a bound cyclin, CDKs perform a common biochemical reaction called phosphorylation that activates or inactivates target proteins to orchestrate coordinated entry into the next phase of the cell cycle. Different cyclin-CDK combinations determine the downstream proteins targeted. CDKs are constitutively expressed in cells whereas cyclins are synthesised at specific stages of the cell cycle, in response to various molecular signals.[14]

text: General mechanism of cyclin-CDK interaction[edit]

text: Upon receiving a pro-mitotic extracellular signal, G1 cyclin-CDK complexes become active to prepare the cell for S phase, promoting the expression of transcription factors that in turn promote the expression of S cyclins and of enzymes required for DNA replication. The G1 cyclin-CDK complexes also promote the degradation of molecules that function as S phase inhibitors by targeting them for ubiquitination. Once a protein has been ubiquitinated, it is targeted for proteolytic degradation by the proteasome. However, results from a recent study of E2F transcriptional dynamics at the single-cell level argue that the role of G1 cyclin-CDK activities, in particular cyclin D-CDK4/6, is to tune the timing rather than the commitment of cell cycle entry.[15]

text: Active S cyclin-CDK complexes phosphorylate proteins that make up the pre-replication complexes assembled during G1 phase on DNA replication origins. The phosphorylation serves two purposes: to activate each already-assembled pre-replication complex, and to prevent new complexes from forming. This ensures that every portion of the cell's genome will be replicated once and only once. The reason for prevention of gaps in replication is fairly clear, because daughter cells that are missing all or part of crucial genes will die. However, for reasons related to gene copy number effects, possession of extra copies of certain genes is also deleterious to the daughter cells.

text: Mitotic cyclin-CDK complexes, which are synthesized but inactivated during S and G2 phases, promote the initiation of mitosis by stimulating downstream proteins involved in chromosome condensation and mitotic spindle assembly. A critical complex activated during this process is a ubiquitin ligase known as the anaphase-promoting complex (APC), which promotes degradation of structural proteins associated with the chromosomal kinetochore. APC also targets the mitotic cyclins for degradation, ensuring that telophase and cytokinesis can proceed.[16]

text: Specific action of cyclin-CDK complexes[edit]

text:
Cyclin D is the first cyclin produced in the cell cycle, in response to extracellular signals (e.g. growth factors). Cyclin D binds to existing CDK4, forming the active cyclin D-CDK4 complex. Cyclin D-CDK4 complex in turn phosphorylates the retinoblastoma susceptibility protein (Rb). The hyperphosphorylated Rb dissociates from the E2F/DP1/Rb complex (which was bound to the E2F responsive genes, effectively "blocking" them from transcription), activating E2F. Activation of E2F results in transcription of various genes like cyclin E, cyclin A, DNA polymerase, thymidine kinase, etc. Cyclin E thus produced binds to CDK2, forming the cyclin E-CDK2 complex, which pushes the cell from G1 to S phase (G1/S, which initiates the G2/M transition).[17] Cyclin B-cdk1 complex activation causes breakdown of nuclear envelope and initiation of prophase, and subsequently, its deactivation causes the cell to exit mitosis.[14]
A quantitative study of E2F transcriptional dynamics at the single-cell level by using engineered fluorescent reporter cells provided a quantitative framework for understanding the control logic of cell cycle entry, challenging the canonical textbook model. Genes that regulate the amplitude of E2F accumulation, such as Myc, determine the commitment in cell cycle and S phase entry. G1 cyclin-CDK activities are not the driver of cell cycle entry. Instead, they primarily tune the timing of E2F increase, thereby modulating the pace of cell cycle progression.[15]

text: Inhibitors[edit]

text: Two families of genes, the cip/kip (CDK interacting protein/Kinase inhibitory protein) family and the INK4a/ARF (Inhibitor of Kinase 4/Alternative Reading Frame) family, prevent the progression of the cell cycle. Because these genes are instrumental in prevention of tumor formation, they are known as tumor suppressors.

text: The cip/kip family includes the genes p21, p27 and p57. They halt cell cycle in G1 phase, by binding to, and inactivating, cyclin-CDK complexes. p21 is activated by p53 (which, in turn, is triggered by DNA damage e.g. due to radiation). p27 is activated by Transforming Growth Factor of β (TGF β), a growth inhibitor.

text: The INK4a/ARF family includes p16INK4a, which binds to CDK4 and arrests the cell cycle in G1 phase, and p14ARF which prevents p53 degradation.

text: Synthetic inhibitors of Cdc25 could also be useful for the arrest of cell cycle and therefore be useful as antineoplastic and anticancer agents.[18]

text: Transcriptional regulatory network[edit]

text: Current evidence suggests that a semi-autonomous transcriptional network acts in concert with the CDK-cyclin machinery to regulate the cell cycle. Several gene expression studies in Saccharomyces cerevisiae have identified 800–1200 genes that change expression over the course of the cell cycle.[13][19][20] They are transcribed at high levels at specific points in the cell cycle, and remain at lower levels throughout the rest of the  cycle. While the set of identified genes differs between studies due to the computational methods and criteria used to identify them, each study indicates that a large portion of yeast genes are temporally regulated.[21]

text: Many periodically expressed genes are driven by transcription factors that are also periodically expressed. One screen of single-gene knockouts identified 48 transcription factors (about 20% of all non-essential transcription factors) that show cell cycle progression defects.[22] Genome-wide studies using high throughput technologies have identified the transcription factors that bind to the promoters of yeast genes, and correlating these findings with temporal expression patterns have allowed the identification of transcription factors that drive phase-specific gene expression.[19][23] The expression profiles of these transcription factors are driven by the transcription factors that peak in the prior phase, and computational models have shown that a CDK-autonomous network of these transcription factors is sufficient to produce steady-state oscillations in gene expression).[20][24]

text: Experimental evidence also suggests that gene expression can oscillate with the period seen in dividing wild-type cells independently of the CDK machinery. Orlando et al. used microarrays to measure the expression of a set of 1,271 genes that they identified as periodic in both wild type cells and cells lacking all S-phase and mitotic cyclins (clb1,2,3,4,5,6). Of the 1,271 genes assayed, 882 continued to be expressed in the cyclin-deficient cells at the same time as in the wild type cells, despite the fact that the cyclin-deficient cells arrest at the border between G1 and S phase. However, 833 of the genes assayed changed behavior between the wild type and mutant cells, indicating that these genes are likely directly or indirectly regulated by the CDK-cyclin machinery. Some genes that continued to be expressed on time in the mutant cells were also expressed at different levels in the mutant and wild type cells. These findings suggest that while the transcriptional network may oscillate independently of the CDK-cyclin oscillator, they are coupled in a manner that requires both to ensure the proper timing of cell cycle events.[20] Other work indicates that phosphorylation, a post-translational modification, of cell cycle transcription factors by Cdk1 may alter the localization or activity of the transcription factors in order to tightly control timing of target genes.[22][25][26]

text: While oscillatory transcription plays a key role in the progression of the yeast cell cycle, the CDK-cyclin machinery operates independently in the early embryonic cell cycle. Before the midblastula transition, zygotic transcription does not occur and all needed proteins, such as the B-type cyclins, are translated from maternally loaded mRNA.[27]

text: DNA replication and DNA replication origin activity[edit]

text: Analyses of synchronized cultures of Saccharomyces cerevisiae under conditions that prevent DNA replication initiation without delaying cell cycle progression showed that origin licensing decreases the expression of genes with origins near their 3' ends, revealing that downstream origins can regulate the expression of upstream genes.[28] This confirms previous predictions from mathematical modeling of a global causal coordination between DNA replication origin activity and mRNA expression,[29][30][31] and shows that mathematical modeling of DNA microarray data can be used to correctly predict previously unknown biological modes of regulation.

text: Checkpoints[edit]

text: Cell cycle checkpoints are used by the cell to monitor and regulate the progress of the cell cycle.[32] Checkpoints prevent cell cycle progression at specific points, allowing verification of necessary phase processes and repair of DNA damage. The cell cannot proceed to the next phase until checkpoint requirements have been met.  Checkpoints typically consist of a network of regulatory proteins that monitor and dictate the progression of the cell through the different stages of the cell cycle.

text: There are several checkpoints to ensure that damaged or incomplete DNA is not passed on to daughter cells. Three main checkpoints exist: the G1/S checkpoint, the G2/M checkpoint and the metaphase (mitotic) checkpoint.

text: G1/S transition is a rate-limiting step in the cell cycle and is also known as restriction point.[14] This is where the cell checks whether it has enough raw materials to fully replicate its DNA (nucleotide bases, DNA synthase, chromatin, etc.). An unhealthy or malnourished cell will get stuck at this checkpoint.

text: The G2/M checkpoint is where the cell ensures that it has enough cytoplasm and phospholipids for two daughter cells. But sometimes more importantly, it checks to see if it is the right time to replicate. There are some situations where many cells need to all replicate simultaneously (for example, a growing embryo should have a symmetric cell distribution until it reaches the mid-blastula transition). This is done by controlling the G2/M checkpoint.

text: The metaphase checkpoint is a fairly minor checkpoint, in that once a cell is in metaphase, it has committed to undergoing mitosis. However that's not to say it isn't important. In this checkpoint, the cell checks to ensure that the spindle has formed and that all of the chromosomes are aligned at the spindle equator before anaphase begins.[33]

text: While these are the three "main" checkpoints, not all cells have to pass through each of these checkpoints in this order to replicate. Many types of cancer are caused by mutations that allow the cells to speed through the various checkpoints or even skip them altogether. Going from S to M to S phase almost consecutively. Because these cells have lost their checkpoints, any DNA mutations that may have occurred are disregarded and passed on to the daughter cells. This is one reason why cancer cells have a tendency to exponentially accrue mutations. Aside from cancer cells, many fully differentiated cell types no longer replicate so they leave the cell cycle and stay in G0 until their death. Thus removing the need for cellular checkpoints. An alternative model of the cell cycle response to DNA damage has also been proposed, known as the postreplication checkpoint.

text: Checkpoint regulation plays an important role in an organism's development. In sexual reproduction, when egg fertilization occurs, when the sperm binds to the egg, it releases signalling factors that notify the egg that it has been fertilized. Among other things, this induces the now fertilized oocyte to return from its previously dormant, G0, state back into the cell cycle and on to mitotic replication and division.

text: p53 plays an important role in triggering the control mechanisms at both G1/S and G2/M checkpoints. In addition to p53, checkpoint regulators are being heavily researched for their roles in cancer growth and proliferation.

text: Fluorescence imaging of the cell cycle[edit]

text: Pioneering work by Atsushi Miyawaki and coworkers developed the fluorescent ubiquitination-based cell cycle indicator (FUCCI), which enables fluorescence imaging of the cell cycle.  Originally, a green fluorescent protein, mAG, was fused to hGem(1/110) and an orange fluorescent protein (mKO2) was fused to hCdt1(30/120).  Note, these fusions are fragments that contain a nuclear localization signal and ubiquitination sites for degradation, but are not functional proteins.  The green fluorescent protein is made during the S, G2, or M phase and degraded during the G0 or G1 phase, while the orange fluorescent protein is made during the G0 or G1 phase and destroyed during the S, G2, or M phase.[34] A far-red and near-infrared FUCCI was developed using a cyanobacteria-derived fluorescent protein (smURFP) and a bacteriophytochrome-derived fluorescent protein (movie found at this link).[35]

text: Role in tumor formation[edit]

text: A disregulation of the cell cycle components may lead to tumor formation.[36] As mentioned above, when some genes like the cell cycle inhibitors, RB, p53 etc. mutate, they may cause the cell to multiply uncontrollably, forming a tumor. Although the duration of cell cycle in tumor cells is equal to or longer than that of normal cell cycle, the proportion of cells that are in active cell division (versus quiescent cells in G0 phase) in tumors is much higher than that in normal tissue.[citation needed] Thus there is a net increase in cell number as the number of cells that die by apoptosis or senescence remains the same.

text: The cells which are actively undergoing cell cycle are targeted in cancer therapy as the DNA is relatively exposed during cell division and hence susceptible to damage by drugs or radiation. This fact is made use of in cancer treatment; by a process known as debulking, a significant mass of the tumor is removed which pushes a significant number of the remaining tumor cells from G0 to G1 phase (due to increased availability of nutrients, oxygen, growth factors etc.). Radiation or chemotherapy following the debulking procedure kills these cells which have newly entered the cell cycle.[14]

text: The fastest cycling mammalian cells in culture, crypt cells in the intestinal epithelium, have a cycle time as short as 9 to 10 hours. Stem cells in resting mouse skin may have a cycle time of more than 200 hours. Most of this difference is due to the varying length of G1, the most variable phase of the cycle. M and S do not vary much.

text: In general, cells are most radiosensitive in late M and G2 phases and most resistant in late S phase.

text: For cells with a longer cell cycle time and a significantly long G1 phase, there is a second peak of resistance late in G1.

text: The pattern of resistance and sensitivity correlates with the level of sulfhydryl compounds in the cell. Sulfhydryls are natural substances that protect cells from radiation damage and tend to be at their highest levels in S and at their lowest near mitosis.


document_title: History of mobile phones

question_text: when did the first portable phone come out

question_tokens: when did the first portable phone come out

root

text: History of mobile phones

text: Predecessors[edit]

text: Before the devices existed that are now referred to as mobile phones or cell phones, there were some precursors. In 1908, a Professor Albert Jahnke and the Oakland Transcontinental Aerial Telephone and Power Company claimed to have developed a wireless telephone. They were accused of fraud and the charge was then dropped, but they do not seem to have proceeded with production.[2] Beginning in 1918, the German railroad system tested wireless telephony on military trains between Berlin and Zossen.[3] In 1924, public trials started with telephone connection on trains between Berlin and Hamburg. In 1925, the company Zugtelephonie AG was founded to supply train telephony equipment and, in 1926, telephone service in trains of the Deutsche Reichsbahn and the German mail service on the route between Hamburg and Berlin was approved and offered to first-class travelers.[4]

tag: p

text: Fiction anticipated the development of real world mobile telephones. In 1906, the English caricaturist Lewis Baumer published a cartoon in Punch magazine entitled "Forecasts for 1907" in which he showed a man and a woman in London's Hyde Park each separately engaged in gambling and dating on wireless telephony equipment.[5] Then, in 1926, the artist Karl Arnold created a visionary cartoon about the use of mobile phones in the street, in the picture "wireless telephony", published in the German satirical magazine Simplicissimus.[6]

text: The Second World War made military use of radio telephony links. Hand-held radio transceivers have been available since the 1940s. Mobile telephones for automobiles became available from some telephone companies in the 1940s. Early devices were bulky, consumed high power, and the network supported only a few simultaneous conversations. Modern cellular networks allow automatic and pervasive use of mobile phones for voice and data communications.

text: In the United States, engineers from Bell Labs began work on a system to allow mobile users to place and receive telephone calls from automobiles, leading to the inauguration of mobile service on 17 June 1946 in St. Louis, Missouri. Shortly after, AT&T offered Mobile Telephone Service. A wide range of mostly incompatible mobile telephone services offered limited coverage area and only a few available channels in urban areas. The introduction of cellular technology, which allowed re-use of frequencies many times in small adjacent areas covered by relatively low powered transmitters, made widespread adoption of mobile telephones economically feasible.

text: In the USSR, Leonid Kupriyanovich, an engineer from Moscow, in 1957-1961 developed and presented a number of experimental models of handheld mobile phones. The weight of one model, presented in 1961, was only 70 g and could fit on a palm.[7][8] However, in the USSR the decision at first to develop the system of the automobile "Altai" phone was made.[9]

text: In 1965, Bulgarian company "Radioelektronika" presented on the Inforga-65 international exhibition in Moscow the mobile automatic phone combined with a base station. Solutions of this phone were based on a system developed by Leonid Kupriyanovich. One base station, connected to one telephone wire line, could serve up to 15 customers.[10]

text: The advances in mobile telephony can be traced in successive generations from the early "0G" services like MTS and its successor Improved Mobile Telephone Service, to first-generation (1G) analog cellular network, second-generation (2G) digital cellular networks, third-generation (3G) broadband data services to the state-of-the-art, fourth-generation (4G) native-IP networks.

text: Early services[edit]

text: MTS[edit]

text: In 1949, AT&T commercialized Mobile Telephone Service. From its start in St. Louis, Missouri, in 1946, AT&T introduced Mobile Telephone Service to one hundred towns and highway corridors by 1948. Mobile Telephone Service was a rarity with only 5,000 customers placing about 30,000 calls each week. Calls were set up manually by an operator and the user had to depress a button on the handset to talk and release the button to listen. The call subscriber equipment weighed about 80 lb.[11]

text: Subscriber growth and revenue generation were hampered by the constraints of the technology. Because only three radio channels were available, only three customers in any given city could make mobile telephone calls at one time.[12] Mobile Telephone Service was expensive, costing 15 USD per month, plus 0.30 to 0.40 USD per local call, equivalent to about 176 USD per month and 3.50 to 4.75 per call in 2012 USD.[11]

text: In the UK, there was also a vehicle-based system called "Post Office Radiophone Service,"[13] which was launched around the city of Manchester in 1959, and although it required callers to speak to an operator, it was possible to be put through to any subscriber in Great Britain. The service was extended to London in 1965 and other major cities in 1972.

text: IMTS[edit]

text: AT&T introduced the first major improvement to mobile telephony in 1965, giving the improved service the obvious name of Improved Mobile Telephone Service. IMTS used additional radio channels, allowing more simultaneous calls in a given geographic area, introduced customer dialing, eliminating manual call setup by an operator, and reduced the size and weight of the subscriber equipment.[11]

text: Despite the capacity improvement offered by IMTS, demand outstripped capacity. In agreement with state regulatory agencies, AT&T limited the service to just 40,000 customers system wide. In New York City, for example, 2,000 customers shared just 12 radio channels and typically had to wait 30 minutes to place a call.[11]

text: Radio Common Carrier[edit]

text: Radio Common Carrier[14] or RCC was a service introduced in the 1960s by independent telephone companies to compete against AT&T's IMTS. RCC systems used paired UHF 454/459 MHz and VHF 152/158 MHz frequencies near those used by IMTS. RCC based services were provided until the 1980s when cellular AMPS systems made RCC equipment obsolete.

text: Some RCC systems were designed to allow customers of adjacent carriers to use their facilities, but equipment used by RCCs did not allow the equivalent of modern "roaming" because technical standards were not uniform. For example, the phone of an Omaha, Nebraska–based RCC service would not be likely to work in Phoenix, Arizona. Roaming was not encouraged, in part, because there was no centralized industry billing database for RCCs. Signaling formats were not standardized. For example, some systems used two-tone sequential paging to alert a mobile of an incoming call. Other systems used DTMF. Some used Secode 2805, which transmitted an interrupted 2805 Hz tone (similar to IMTS signaling) to alert mobiles of an offered call. Some radio equipment used with RCC systems was half-duplex, push-to-talk LOMO equipment such as Motorola hand-helds or RCA 700-series conventional two-way radios. Other vehicular equipment had telephone handsets and rotary dials or pushbutton pads, and operated full duplex like a conventional wired telephone. A few users had full-duplex briefcase telephones (radically advanced for their day)

text: At the end of RCC's existence, industry associations were working on a technical standard that would have allowed roaming, and some mobile users had multiple decoders to enable operation with more than one of the common signaling formats (600/1500, 2805, and Reach). Manual operation was often a fallback for RCC roamers.

text: Other services[edit]

text: In 1969 Penn Central Railroad equipped commuter trains along the 360 km New York-Washington route with special pay phones that allowed passengers to place telephone calls while the train was moving. The system re-used six frequencies in the 450 MHz band in nine sites.[12]

text: In the UK, Channel Islands and elsewhere the "Rabbit" phone system was briefly used, being a hybrid of "cell" base stations and handsets. One major limitation was that you had to be less than 300 feet (closer with buildings) from a base due to power limitations on a portable device. [15][better source needed] With modern technology a similar variant is being considered for Apple's new 4G "smart watch" so they can be used in large events in a broadly similar way to a femtocell.

text: European mobile radio networks[edit]

text: This section needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (April 2012) (Learn how and when to remove this template message)

tag: table

text: In Europe, several mutually incompatible mobile radio services were developed.

text: In 1966 Norway had a system called OLT which was manually controlled. Finland's ARP, launched in 1971, was also manual as was the Swedish MTD. All were replaced by the automatic NMT, (Nordic Mobile Telephone) system in the early 1980s.

text: In July 1971 Readycall was introduced in London by Burndept after obtaining a special concession to break the Post Office monopoly to allow selective calling to mobiles of calls from the public telephone system. This system was available to the public for a subscription of £16 month. A year later the service was extended to two other UK towns.[16]

text: West Germany had a network called A-Netz launched in 1952 as the country's first public commercial mobile phone network. In 1972 this was displaced by B-Netz which connected calls automatically.

text: The cellular concept[edit]

text: In December 1947, Douglas H. Ring and W. Rae Young, Bell Labs engineers, proposed hexagonal cells for mobile phones in vehicles.[17] At this stage, the technology to implement these ideas did not exist, nor had the frequencies been allocated. Two decades would pass before Richard H. Frenkiel, Joel S. Engel and Philip T. Porter of Bell Labs expanded the early proposals into a much more detailed system plan. It was Porter who first proposed that the cell towers use the now-familiar directional antennas to reduce interference and increase channel reuse (see picture at right)[18] Porter also invented the dial-then-send method used by all cell phones to reduce wasted channel time.

text: In all these early examples, a mobile phone had to stay within the coverage area serviced by one base station throughout the phone call, i.e. there was no continuity of service as the phones moved through several cell areas. The concepts of frequency reuse and handoff, as well as a number of other concepts that formed the basis of modern cell phone technology, were described in the late 1960s, in papers by Frenkiel and Porter. In 1970 Amos E. Joel, Jr., a Bell Labs engineer,[19] invented a "three-sided trunk circuit" to aid in the "call handoff" process from one cell to another. His patent contained an early description of the Bell Labs cellular concept, but as switching systems became faster, such a circuit became unnecessary and was never implemented in a system.

text: A cellular telephone switching plan was described by Fluhr and Nussbaum in 1973,[20] and a cellular telephone data signaling system was described in hipatitas by Hachenburg et al.[21]

text: Emergence of automated services[edit]

text: The first fully automated mobile phone system for vehicles was launched in Sweden in 1956. Named MTA (Mobiltelefonisystem A), it allowed calls to be made and received in the car using a rotary dial. The car phone could also be paged. Calls from the car were direct dial, whereas incoming calls required an operator to locate the nearest base station to the car. It was developed by Sture Laurén and other engineers at Televerket network operator. Ericsson provided the switchboard while Svenska Radioaktiebolaget (SRA) and Marconi provided the telephones and base station equipment. MTA phones consisted of vacuum tubes and relays, and weighed 40 kg. In 1962, an upgraded version called Mobile System B (MTB) was introduced. This was a push-button telephone, and used transistors and DTMF signaling to improve its operational reliability. In 1971 the MTD version was launched, opening for several different brands of equipment and gaining commercial success.[22][23] The network remained open until 1983 and still had 600 customers when it closed.

text: In 1958 development began on a similar system for motorists in the USSR.[24] The "Altay" national civil mobile phone service was based on Soviet MRT-1327 standard. The main developers of the Altay system were the Voronezh Science Research Institute of Communications (VNIIS) and the State Specialized Project Institute (GSPI). In 1963 the service started in Moscow, and by 1970 was deployed in 30 cities across the USSR. Versions of the Altay system are still in use today as a trunking system in some parts of Russia.

text: In 1959 a private telephone company in Brewster, Kansas, USA, the S&T Telephone Company, (still in business today) with the use of Motorola Radio Telephone equipment and a private tower facility, offered to the public mobile telephone services in that local area of NW Kansas. This system was a direct dial up service through their local switchboard, and was installed in many private vehicles including grain combines, trucks, and automobiles. For some as yet unknown reason, the system, after being placed online and operated for a very brief time period, was shut down. The management of the company was immediately changed, and the fully operable system and related equipment was immediately dismantled in early 1960, not to be seen again.[citation needed]

text: In 1966, Bulgaria presented the pocket mobile automatic phone RAT-0,5 combined with a base station RATZ-10 (RATC-10) on Interorgtechnika-66 international exhibition. One base station, connected to one telephone wire line, could serve up to six customers ("Radio" magazine, 2, 1967; "Novosti dnya" newsreel, 37, 1966).

text: One of the first successful public commercial mobile phone networks was the ARP network in Finland, launched in 1971. Posthumously, ARP is sometimes viewed as a zero generation (0G) cellular network, being slightly above previous proprietary and limited coverage networks.[citation needed]

text: Handheld mobile phone[edit]

text: Prior to 1973, mobile telephony was limited to phones installed in cars and other vehicles.[19] Motorola was the first company to produce a handheld mobile phone. On April 3, 1973, Martin Cooper, a Motorola researcher and executive, made the first mobile telephone call from handheld subscriber equipment, placing a call to Dr. Joel S. Engel of Bell Labs, his rival.[25][26] The prototype handheld phone used by Dr. Cooper weighed 1.1 kg (2.42 lb) and measured 23 cm long, 13 cm deep and 4.45 cm wide. The prototype offered a talk time of just 30 minutes and took 10 hours to re-charge.[27]

text: John F. Mitchell,[28][29][30] Motorola's chief of portable communication products and Cooper's boss in 1973, played a key role in advancing the development of handheld mobile telephone equipment. Mitchell successfully pushed Motorola to develop wireless communication products that would be small enough to use anywhere and participated in the design of the cellular phone.[31][32]

text: The early generations[edit]

text: Newer technology has been developed and rolled out in a series of waves or generations. The "generation" terminology only became widely used when 3G was launched, but is now used retroactively when referring to the earlier systems.

text: 1G – Analogue cellular[edit]

text: First automatic analogue cellular systems deployed were NTT's system first used in Tokyo in 1979, later spreading to the whole of Japan, and NMT in the Nordic countries in 1981.

text: The first analogue cellular system widely deployed in North America was the Advanced Mobile Phone System (AMPS).[33] It was commercially introduced in the Americas in 13 October 1983, Israel in 1986, and Australia in 1987. AMPS was a pioneering technology that helped drive mass market usage of cellular technology, but it had several serious issues by modern standards. It was unencrypted and easily vulnerable to eavesdropping via a scanner; it was susceptible to cell phone "cloning" and it used a Frequency-division multiple access (FDMA) scheme and required significant amounts of wireless spectrum to support.

text: On 6 March 1983, the DynaTAC 8000X mobile phone launched on the first US 1G network by Ameritech. It cost $100m to develop, and took over a decade to reach the market.[34] The phone had a talk time of just thirty-five minutes and took ten hours to charge. Consumer demand was strong despite the battery life, weight, and low talk time, and waiting lists were in the thousands.[35][36]

text: Many of the iconic early commercial cell phones such as the Motorola DynaTAC Analog AMPS were eventually superseded by Digital AMPS (D-AMPS) in 1990, and AMPS service was shut down by most North American carriers by 2008.

text: In February 1986 Australia launched its Cellular Telephone System by Telecom Australia. Peter Reedman was the first Telecom Customer to be connected on 6 January 1986 along with five other subscribers as test customers prior to the official launch date of 28 February.

text: 2G – Digital cellular[edit]

text: In the 1990s, the 'second generation' mobile phone systems emerged. Two systems competed for supremacy in the global market: the European developed GSM standard and the U.S. developed CDMA standard. These differed from the previous generation by using digital instead of analog transmission, and also fast out-of-band phone-to-network signaling. The rise in mobile phone usage as a result of 2G was explosive and this era also saw the advent of prepaid mobile phones.

text: In 1991 the first GSM network (Radiolinja) launched in Finland. In general the frequencies used by 2G systems in Europe were higher than those in America, though with some overlap. For example, the 900 MHz frequency range was used for both 1G and 2G systems in Europe, so the 1G systems were rapidly closed down to make space for the 2G systems. In America the IS-54 standard was deployed in the same band as AMPS and displaced some of the existing analog channels.

text: In 1993, IBM Simon was introduced. This was possibly the world's first smartphone. It was a mobile phone, pager, fax machine, and PDA all rolled into one. It included a calendar, address book, clock, calculator, notepad, email, and a touchscreen with a QWERTY keyboard.[37] The IBM Simon had a stylus you used to tap the touch screen with. It featured predictive typing that would guess the next characters as you tapped. It had applications, or at least a way to deliver more features by plugging a PCMCIA 1.8 MB memory card into the phone.[38] Coinciding with the introduction of 2G systems was a trend away from the larger "brick" phones toward tiny 100 – 200 gram hand-held devices. This change was possible not only through technological improvements such as more advanced batteries and more energy-efficient electronics, but also because of the higher density of cell sites to accommodate increasing usage. The latter meant that the average distance transmission from phone to the base station shortened, leading to increased battery life while on the move.

text: The second generation introduced a new variant of communication called SMS or text messaging. It was initially available only on GSM networks but spread eventually on all digital networks. The first machine-generated SMS message was sent in the UK on 3 December 1992 followed in 1993 by the first person-to-person SMS sent in Finland. The advent of prepaid services in the late 1990s soon made SMS the communication method of choice among the young, a trend which spread across all ages.

text: 2G also introduced the ability to access media content on mobile phones. In 1998 the first downloadable content sold to mobile phones was the ring tone, launched by Finland's Radiolinja (now Elisa). Advertising on the mobile phone first appeared in Finland when a free daily SMS news headline service was launched in 2000, sponsored by advertising.

text: Mobile payments were trialed in 1998 in Finland and Sweden where a mobile phone was used to pay for a Coca-Cola vending machine and car parking. Commercial launches followed in 1999 in Norway. The first commercial payment system to mimic banks and credit cards was launched in the Philippines in 1999 simultaneously by mobile operators Globe and Smart.

text: The first full internet service on mobile phones was introduced by NTT DoCoMo in Japan in 1999.

text: 3G – Mobile broadband[edit]

text: As the use of 2G phones became more widespread and people began to use mobile phones in their daily lives, it became clear that demand for data (such as access to browse the internet) was growing. Further, experience from fixed broadband services showed there would also be an ever-increasing demand for greater data speeds. The 2G technology was nowhere near up to the job, so the industry began to work on the next generation of technology known as 3G. The main technological difference that distinguishes 3G technology from 2G technology is the use of packet switching rather than circuit switching for data transmission.[39] In addition, the standardization process focused on requirements more than technology (2 Mbit/s maximum data rate indoors, 384 kbit/s outdoors, for example).

text: Inevitably this led to many competing standards with different contenders pushing their own technologies, and the vision of a single unified worldwide standard looked far from reality. The standard 2G CDMA networks became 3G compliant with the adoption of Revision A to EV-DO, which made several additions to the protocol while retaining backwards compatibility:

text:
Introduction of several new forward link data rates that increase the maximum burst rate from 2.45 Mbit/s to 3.1 Mbit/s
Protocols that would decrease connection establishment time
Ability for more than one mobile to share the same time slot
Introduction of QoS flags

tag: ul

text: All these were put in place to allow for low latency, low bit rate communications such as VoIP.[40]

text: The first pre-commercial trial network with 3G was launched by NTT DoCoMo in Japan in the Tokyo region in May 2001. NTT DoCoMo launched the first commercial 3G network on 1 October 2001, using the WCDMA technology. In 2002 the first 3G networks on the rival CDMA2000 1xEV-DO technology were launched by SK Telecom and KTF in South Korea, and Monet in the US. Monet has since gone bankrupt. By the end of 2002, the second WCDMA network was launched in Japan by Vodafone KK (now Softbank). European launches of 3G were in Italy and the UK by Three/Hutchison group, on WCDMA. 2003 saw a further eight commercial launches of 3G, six more on WCDMA and two more on the EV-DO standard.

text: During the development of 3G systems, 2.5G systems such as CDMA2000 1x and GPRS were developed as extensions to existing 2G networks. These provide some of the features of 3G without fulfilling the promised high data rates or full range of multimedia services. CDMA2000-1X delivers theoretical maximum data speeds of up to 307 kbit/s. Just beyond these is the EDGE system which in theory covers the requirements for 3G system, but is so narrowly above these that any practical system would be sure to fall short.

text: The high connection speeds of 3G technology enabled a transformation in the industry: for the first time, media streaming of radio (and even television) content to 3G handsets became possible,[41] with companies such as RealNetworks[42] and Disney[43] among the early pioneers in this type of offering.

text: In the mid-2000s (decade), an evolution of 3G technology began to be implemented, namely High-Speed Downlink Packet Access (HSDPA). It is an enhanced 3G (third generation) mobile telephony communications protocol in the High-Speed Packet Access (HSPA) family, also coined 3.5G, 3G+ or turbo 3G, which allows networks based on Universal Mobile Telecommunications System (UMTS) to have higher data transfer speeds and capacity. Current HSDPA deployments support down-link speeds of 1.8, 3.6, 7.2 and 14.0 Mbit/s.

text: By the end of 2007, there were 295 million subscribers on 3G networks worldwide, which reflected 9% of the total worldwide subscriber base. About two thirds of these were on the WCDMA standard and one third on the EV-DO standard. The 3G telecoms services generated over $120 billion of revenues during 2007 and at many markets the majority of new phones activated were 3G phones. In Japan and South Korea the market no longer supplies phones of the second generation.

text: Although mobile phones had long had the ability to access data networks such as the Internet, it was not until the widespread availability of good quality 3G coverage in the mid-2000s (decade) that specialized devices appeared to access the mobile web. The first such devices, known as "dongles", plugged directly into a computer through the USB port. Another new class of device appeared subsequently, the so-called "compact wireless router" such as the Novatel MiFi, which makes 3G Internet connectivity available to multiple computers simultaneously over Wi-Fi, rather than just to a single computer via a USB plug-in.

text: Such devices became especially popular for use with laptop computers due to the added portability they bestow. Consequently, some computer manufacturers started to embed the mobile data function directly into the laptop so a dongle or MiFi wasn't needed. Instead, the SIM card could be inserted directly into the device itself to access the mobile data services. Such 3G-capable laptops became commonly known as "netbooks". Other types of data-aware devices followed in the netbook's footsteps. By the beginning of 2010, E-readers, such as the Amazon Kindle and the Nook from Barnes & Noble, had already become available with embedded wireless Internet, and Apple had announced plans for embedded wireless Internet on its iPad tablet devices later that year.

text: 4G – Native IP networks[edit]

text: By 2009, it had become clear that, at some point, 3G networks would be overwhelmed by the growth of bandwidth-intensive applications like streaming media.[44] Consequently, the industry began looking to data-optimized 4th-generation technologies, with the promise of speed improvements up to 10-fold over existing 3G technologies. The first two commercially available technologies billed as 4G were the WiMAX standard (offered in the U.S. by Sprint) and the LTE standard, first offered in Scandinavia by TeliaSonera.

text: One of the main ways in which 4G differed technologically from 3G was in its elimination of circuit switching, instead employing an all-IP network. Thus, 4G ushered in a treatment of voice calls just like any other type of streaming audio media, utilizing packet switching over Internet, LAN or WAN networks via VoIP.[45]

text: Mobile device charger standards[edit]

text:
USB power standards for mobile charger

Port
Current
Voltage
Power (max)

Micro-USB
500 mA
5 V
2.5 W

1 A
5 V
5 W

2 A
5 V
10 W

Type-C[46]
100 mA to 3 A
5 V
15 W

1.7 A to 3 A
9 V
27 W

1.8 A to 3 A
15 V
45 W

2.25 A to 5 A
20 V
100 W

text: Before a universal charger standard was agreed upon in the late 2000s users needed an adaptor which was often the same brand as their phone to recharge the battery.

text: In China[edit]

text: As of 14 June 2007[update], all new mobile phones applying for a license in China are required to use a USB port as a power port for battery charging.[47][48] This was the first standard to use the convention of shorting D+ and D−.[49]

text: OMTP/GSMA Universal Charging Solution[edit]

text: In September 2007, the Open Mobile Terminal Platform group (a forum of mobile network operators and manufacturers such as Nokia, Samsung, Motorola, Sony Ericsson, and LG) announced that its members had agreed on Micro-USB as the future common connector for mobile devices.[50][51]

text: The GSM Association (GSMA) followed suit on 17 February 2009,[52][52][53][54][55] and on 22 April 2009, this was further endorsed by the CTIA – The Wireless Association,[56] with the International Telecommunication Union (ITU) announcing on 22 October 2009 that it had also embraced the Universal Charging Solution as its "energy-efficient one-charger-fits-all new mobile phone solution," and added: "Based on the Micro-USB interface, UCS chargers will also include a 4-star or higher efficiency rating—up to three times more energy-efficient than an unrated charger."[57]

text: EU smartphone power supply standard[edit]

text: In June 2009, many of the world's largest mobile phone manufacturers signed an EC-sponsored Memorandum of Understanding (MoU), agreeing to make most data-enabled mobile phones marketed in the European Union compatible with a common External Power Supply (common EPS). The EU's common EPS specification (EN 62684:2010) references the USB Battery Charging Specification and is similar to the GSMA/OMTP and Chinese charging solutions.[58][59] In January 2011, the International Electrotechnical Commission (IEC) released its version of the (EU's) common EPS standard as IEC 62684:2011.[60]

text: Satellite mobile[edit]

text: As well as the now-common cellular phone, there is also the very different approach of connecting directly from the handset to an Earth-orbiting satellite. Such mobile phones can be used in remote areas out of reach of wired networks or where construction of a cellular network is uneconomic.

text: The Inmarsat system is the oldest, originally developed in 1979 for safety of life at sea, and uses a series of satellites in geostationary orbits to cover the majority of the globe. Several smaller operators use the same approach with just one or two satellites to provide a regional service. An alternative approach is to use a series of low Earth orbit satellites much closer to Earth. This is the basis of the Iridium and Globalstar satellite phone services.


document_title: Spanish missions in the Americas

question_text: who are the franciscans and why did they go to texas

text: Spanish missions in the Americas

text: Introduction[edit]

text: At the start of the Age of Discovery, European governments sent explorers to find trade routes to facilitate economic relations with Asia and Europe. During this time, these men found the new lands that could be used for the economic benefit of their home countries. In order to understand these new lands and the resources that might be available, explorers fostered relationships with the native people. This led to the colonization of the Americas. The Catholic Church was an essential part of both the Spanish and Portuguese Empires so as the empires spread to new lands, it was the duty of the King to be sure Christianity was spread into the New World.

text: Often these empires used missions to teach indigenous people about Christian values that were practised in Europe at this time.  These values did not only include religious teachings but cultural aspects of life such as dress and behavior. Missions were formed in different ways across the Americas that have had a lasting impact on the culture of these areas. Catholicism is still a prevalent religion in both North and South America. The formation and implementation of the missions across the New World reflected the beliefs of the Catholic clerics who created and implemented the missions. In the Catholic church, monks, priests and other clerics take vows and are affiliated with a certain order. These orders, their ideologies, and era can be linked to the way of life and teaching in the missions.

text: Despite extensive efforts and even successes in recovering the cultural history of the cultures colonized in the Americas, much of the evidence currently available comes from the colonizers themselves. Many of the cultures impacted by missionaries had no written language and were thus robbed of much of their oral history when the populations were decimated by Old World illnesses.[1] Cultures that did possess written language, such as the Maya, often had their artifacts deemed sacrilegious and burned.[2] Therefore, much of the evidence of these events comes from accounts of missionaries and—to a much smaller extent—archaeological investigation, and should be handled with care. Therefore, readers should consider the ethnocentric and theocratic context in which accounts recorded by missionaries are presented.

text: Spanish colonialism[edit]

text: Practices[edit]

text: Catholic missions were installed throughout the Americas in an effort to establish European order in the pursuit of gold, silver, and other resources. The missionaries' goal was to convert natives to Christianity and ease the transition into a colonial system and minimize the friction required to establish European dominance in the area.[3] One symbolic example of this was the practice of constructing churches and cathedrals, such as Santa Domingo and Cathedral Basilica of Our Lady of the Assumption, on top of demolished native temples.[4] Establishment of missions was often followed by the implementation of Encomienda systems, which forced native labor onto land granted to Europeans by the Spanish Crown and led to systematic oppression.

text: Spanish Missionaries[edit]

text: Pedro de Gante was a European missionary who desired assimilation of Native American communities in order to further educational discourse amongst indigenous communities. He was so influential in his work, he became known as "The first teacher of the Americas" (Campos, 89). Originally, Peeter Van der Moere, Pedro de Gante, came to "New Spain," in 1523 also known as Mexico. A missionary, Pedro de Gante, wanted to spread the Christian faith to his native brothers and sisters. During this time, the mentality of the Spanish people was to not empower the indigenous people with knowledge because it would give them motivation to retaliate over their Spanish rulers. Nevertheless, Pedro de Gante saw the ritualistic practices being made by the indigenous, sacrificing animals, and as a missionary, saw the need for a change in faith. He decided in order to best approach theses indigenous communities he had to adapt to their way of life. He learned their native tongue and participated in their conversations and games (Lipp, 194). Despite having a stutter, he was a successful translator of Nahuatl and Spanish (Campos, 89). Additionally, Pedro de Gante was a big advocate of education of the youth, where he established schools throughout Mexico to cater to the indigenous communities (Britannica, 1998). His influence spanned so wide, others like him followed by example. Of the future missionaries to come to America, at least three of his compatriots came (Proano, 1972).

text: Native revolts[edit]

text: In addition to the encomienda system, the aggressive implementation of missions and their forcible establishment of reductions and congregations led to resistance and sometimes revolt in the native populations being colonized. Many natives agreed to join the reductions and congregations out of fear, but many were initially still allowed to quietly continue some of their religious practices. However, as treatment of natives grew worse and suppression of native customs increased, so did the resistance of the natives.

text: The most notable example of rebellion against colonization is the Pueblo Revolt in 1680, in which the Zuni, Hopi, as well as Tiwa, Tewa, Towa, Tano, and Keres-speaking Pueblos took control of Santa Fe and drove the Spanish colonial presence out of New Mexico with heavy casualties on the Spanish side, including 21 of the 33 Franciscan missionaries in New Mexico. The region remained autonomous under native control despite multiple non-violent attempts at peace treaties and trade agreements until 1692.

text: The Tepehuan Revolt was likewise stirred by hostilities against the missionaries, which arose due to the concurrent and explosive rise in disease that accompanied their arrival.[5] The Tepehuan associated the rise in death directly with these missionaries and their reductions, which spread disease and facilitated exploitative labor to encomanderos and miners.[6] The revolt lasted from 1616 to 1620 with heavy casualties on both sides, during which time the Spanish abandoned their policy of "peace by purchase (tribute)" in favor of "war of fire and blood".[7]

text: Epidemics in Missions[edit]

text: With resistance and revolts, the native population dropped drastically with the introduction of Spanish missions. However, the main factor for the overwhelming losses were due to epidemics in the missions. Despite being affected before the introduction of missions, the buildings allowed rodents to infiltrate living areas and spread disease more rapidly. Many natives were living in cramped spaces with poor hygiene and poor nutrition. This led not only to high mortality rate, but to low fertility rates as well. It is estimated that every 20 years or so, a new epidemic would wipe out the adult population of natives in many missions, giving no chance for recovery. (Newson, 2005)

text: Cultural Changes[edit]

text: In converting natives, missionaries had to find various ways of implementing sacramental practices among them. Some sacraments, like Baptism, were already similar to the Nahuatl rituals during birth, usually performed by a midwife. Many missionaries even allowed for natives to keep some aspects of their original ritual in place, like giving the child or newborn a small arrowhead or broom to represent their future roles in society, as long as it complied with Catholic beliefs. Other sacraments, like Matrimony, were fairly different from native practices. Many natives were polygamous and to perform the sacrament of marriage, Franciscan monks would have a husband bring his many wives to the church, having them all state their reasons for being the one true wife. The monks would then decide based on the testimony who was his wife and perform the sacrament. (Reilly, 2016)

text: In addition to religious changes, Spanish missionaries also brought about secular changes. With each generation of natives, there was a gradual shift in what they ate, wore and how the economy within the missions worked. Missionaries introduced adobe style houses for nomadic natives and domesticated animals for meat rather than wild game. The Spanish colonists also brought more foods and plants from Europe and South American to regions that initially had no contact with nations there. Natives began to dress in European-style clothing and adopted the Spanish language, often morphing it with Nahuatl and other native languages. (Jackson,1995)

text: Catholic Orders[edit]

text: Franciscan[edit]

text: Franciscan missionaries were the first to arrive in New Spain, in 1523, following the Cortes expeditions in Mexico, and soon after began establishing missions across the continents.[8][9] In addition to their primary goal of spreading Christianity, the missionaries studied the native languages, taught children to read and write, and taught adults trades such as carpentry and ceramics. The first missionaries to arrive in the New World were Franciscan monks from the observant faction which believed in a strict and limited way of practicing religion. Because the monks believed teaching and practicing can only be done through "meditation and contemplation", Franciscans were not able to convert as many people as quickly as the Spanish would have liked. This caused strain between colonial governments and Franciscan friars, which eventually led to several of the friars fleeing to present day western Mexico and the dissolution of Franciscan parishes. Other issues also contributed to the dissolution of Franciscan parishes including the vow of poverty and accusations made by the colonial governments. However, Spanish missions often used money provided by the King to fund missions. Having monks taking money proved to be a controversial issue within the church. In addition, the colonial government claimed missionaries were mistreating indigenous people who were working on the missions. On the other hand, the Franciscan missionaries claimed that the Spanish government enslaved and mistreated indigenous people. Present day efforts are to show where Franciscan missionaries protected the indigenous people from Spanish cruelties and supported empowering the native peoples.[10]

text: Jesuits[edit]

text: The Jesuits had a wide-spread impact between their arrival in the New World about 1570 until their expulsion in 1767. The Jesuits, especially in the southeastern part of South America, followed a widespread Spanish practice of creating settlements called "reductions" to concentrate the widespread native populations in order to better rule, Christianize, and protect the native populace.[11] The Jesuit Reductions were socialist societies in which each family would receive a house and field, and individuals were clothed and fed in return for work. Additionally, the communities would include schools, churches, and hospitals as well as native leaders and governing councils to be overseen by two Jesuit missionaries in each reduction. Like the Franciscans, the Jesuit missionaries learned the local languages and trained the adults in European methods of construction, manufacturing, and, to a certain extent, agriculture.[12] Spanish settlers were prohibited from living or working in reductions. This led to a strained relationship between Jesuit missionaries and the Spanish because in surrounding Spanish settlements people were not guaranteed food, shelter, and clothing.[13]

text: Another major Jesuit effort was that of Eusebio Kino S.J., in the region then known as the Pimería Alta – modern-day Sonora in Mexico and southern Arizona in the United States. [14]

text: Dominicans[edit]

text: The Dominicans were centralized in the Caribbean and Mexico and, despite a much smaller representation in the Americas, had one of the most notable histories of native rights activism. Bartolomé de las Casas was the first Dominican bishop in Mexico and played a pivotal role in dismantling the practice of "encomenderos",these laws were intended to prevent the exploitation and mistreatment of the indigenous peoples of the Americas by the encomenderos, by strictly limiting their power and dominion over groups of natives, with the establishment of the New Laws in 1542.[15]


document_title: Figure skating at the 2018 Winter Olympics – Men's singles

question_text: who won the men's figure skating 2018 olympics

question_tokens: who won the men 's figure skating 2018 olympics

text: Summary[edit]

text: With his victory at the 2018 Winter Olympics, Yuzuru Hanyu became the first male figure skater to win two consecutive gold medals after Dick Button, who did so in 1952. Fellow countryman Shoma Uno won the silver medal, and Spain's Javier Fernández won the bronze medal. Fernández won Spain's first figure skating medal and fourth medal at the Winter Olympics.

text: After the short program, Hanyu, Fernández, Uno, and Jin Boyang were first, second, third, and fourth respectively. Nathan Chen, originally one of the favorites for the podium, skated an uncharacteristically poor short program that placed him at 17th, but fought back to win the free skating with a score of 215.08--8.91 points above the second place free skating by Hanyu. He ended up fifth overall. In the free program, Jin Boyang overtook Chen by less than a point overall, and placed fourth.

text: In the victory ceremony, the medals were presented by Tsunekazu Takeda, member of the International Olympic Committee, accompanied by Alexander Lakernik, ISU Figure Skating Vice President.

text: Vincent Zhou landed the first quadruple lutz at the Olympics. Nathan Chen became the first to ever land six quads, five clean. He also landed the first quadruple flip at the Olympics. [5] With these jumps he holds the new record for highest free skating technical score.[6] For complete list of figure skating records, see list of highest scores in figure skating.

text: Qualification[edit]

text: A total of 30 skaters qualified to compete for the event, with each country allowed to only enter a maximum of three. 24 quotas were handed out during the 2017 World Figure Skating Championships and the remaining six were given out at the 2017 CS Nebelhorn Trophy. Each country decided the entry of its teams, and athletes winning the quota were not necessarily granted the right to compete.[7] All athletes competing must have met the minimum total elements score, which does not include component scores. For the short program this was 25.00 and the free skating 45.00.[8]

text: Schedule[edit]

text: All times are (UTC+9).

text:
Date
Time
Round

16 February
10:00[3]
Short program

17 February
10:00[3]
Free skating

text: Results[edit]

text: Short program[edit]

text: The short program was held on 16 February 2018.[3][9]

text:
Pl.
Name
Nation
TSS
TES
PCS
SS
TR
PE
CH
IN
Ded
StN

1
Yuzuru Hanyu
 Japan
111.68
63.18
48.50
9.71
9.43
9.86
9.75
9.75
0.00
25

2
Javier Fernández
 Spain
107.58
59.79
47.79
9.36
9.36
9.71
9.68
9.68
0.00
29

3
Shoma Uno
 Japan
104.17
58.13
46.04
9.29
9.00
9.25
9.29
9.21
0.00
28

4
Jin Boyang
 China
103.32
60.27
43.05
8.79
8.29
8.82
8.54
8.61
0.00
30

5
Dmitri Aliev
 Olympic Athletes from Russia
98.98
56.98
42.00
8.43
8.11
8.50
8.50
8.46
0.00
20

6
Patrick Chan
 Canada
90.01
45.08
45.93
9.36
9.07
9.00
9.29
9.21
–1.00
21

7
Adam Rippon
 United States
87.95
44.48
43.47
8.57
8.43
8.86
8.68
8.93
0.00
19

8
Mikhail Kolyada
 Olympic Athletes from Russia
86.69
43.84
43.85
8.96
8.54
8.64
8.82
8.89
–1.00
27

9
Michal Březina
 Czech Republic
85.15
44.34
40.81
8.25
7.89
8.25
8.21
8.21
0.00
13

10
Keegan Messing
 Canada
85.11
45.50
40.61
8.04
7.96
8.07
8.29
8.25
−1.00
12

11
Jorik Hendrickx
 Belgium
84.74
44.17
40.57
7.96
7.89
8.25
8.18
8.29
0.00
17

12
Vincent Zhou
 United States
84.53
48.50
36.03
7.39
6.96
7.11
7.32
7.25
0.00
3

13
Oleksii Bychenko
 Israel
84.13
43.63
40.50
7.93
7.71
8.36
8.18
8.32
0.00
23

14
Misha Ge
 Uzbekistan
83.90
41.75
42.15
8.18
8.18
8.54
8.46
8.79
0.00
16

15
Cha Jun-hwan
 South Korea
83.43
43.79
39.64
7.93
7.68
8.07
8.00
7.96
0.00
14

16
Brendan Kerry
 Australia
83.06
45.49
37.57
7.57
7.36
7.61
7.57
7.46
0.00
10

17
Nathan Chen
 United States
82.27
41.39
41.88
8.46
8.32
8.14
8.57
8.39
–1.00
26

18
Daniel Samohin
 Israel
80.69
43.29
38.40
7.79
7.29
7.79
7.71
7.82
–1.00
18

19
Yan Han
 China
80.63
40.99
40.64
8.46
8.07
7.86
8.18
8.07
−1.00
8

20
Keiji Tanaka
 Japan
80.05
40.30
40.75
8.36
7.86
8.07
8.21
8.25
–1.00
22

21
Deniss Vasiļjevs
 Latvia
79.52
39.34
41.18
8.25
8.00
8.18
8.39
8.36
–1.00
24

22
Moris Kvitelashvili
 Georgia
76.56
40.88
36.68
7.46
7.11
7.32
7.43
7.36
−1.00
11

23
Matteo Rizzo
 Italy
75.63
39.23
36.40
7.29
7.11
7.29
7.39
7.32
0.00
5

24
Paul Fentz
 Germany
74.73
37.71
37.02
7.46
7.25
7.46
7.46
7.39
0.00
15

Did not advance to free skating

25
Julian Yee
 Malaysia
73.58
38.37
35.21
7.07
6.82
7.11
7.14
7.07
0.00
9

26
Chafik Besseghier
 France
72.10
38.41
33.69
6.79
6.29
6.89
6.86
6.86
0.00
2

27
Denis Ten
 Kazakhstan
70.12
30.77
39.35
8.11
7.82
7.46
8.07
7.89
0.00
4

28
Michael Christian Martinez
 Philippines
55.56
26.04
29.52
5.96
5.64
5.96
6.00
5.96
0.00
6

29
Felipe Montoya
 Spain
52.41
22.59
30.82
6.25
6.07
6.00
6.25
6.25
−1.00
1

30
Yaroslav Paniot
 Ukraine
46.58
18.68
29.90
6.43
5.79
5.61
6.21
5.86
−2.00
7

text:
Notes:
WR - World record
TSS - Total Segment Score; TES - Technical Element Score; PCS - Program Component Score
SS - Skating Skills; TR - Transitions; PE - Performance/Execution
CH - Choreography; IN - Interpretation; Ded - Deduction; StN - Starting Number

text: Free skating[edit]

text: The free skating was held on 17 February 2018.[3][10]

text:
Pl.
Name
Nation
TSS
TES
PCS
SS
TR
PE
CH
IN
Ded
StN

1
Nathan Chen
 United States
215.08
127.64
87.44
8.82
8.32
9.04
8.79
8.75
0.00
9

2
Yuzuru Hanyu
 Japan
206.17
109.55
96.62
9.71
9.50
9.64
9.71
9.75
0.00
22

3
Shoma Uno
 Japan
202.73
111.01
92.72
9.36
9.07
9.25
9.32
9.36
–1.00
24

4
Javier Fernández
 Spain
197.66
101.52
96.14
9.46
9.43
9.64
9.79
9.75
0.00
23

5
Jin Boyang
 China
194.45
109.69
85.76
8.71
8.21
8.64
8.68
8.64
–1.00
20

6
Vincent Zhou
 United States
192.16
112.24
79.92
8.04
7.71
8.25
7.96
8.00
0.00
15

7
Mikhail Kolyada
 Olympic Athletes from Russia
177.56
91.62
87.94
9.00
8.64
8.68
8.86
8.72
–2.00
16

8
Patrick Chan
 Canada
173.42
81.56
91.86
9.32
9.14
8.66
9.29
9.32
0.00
21

9
Oleksii Bychenko
 Israel
172.88
89.08
83.80
8.39
8.04
8.61
8.43
8.43
0.00
7

10
Adam Rippon
 United States
171.41
84.47
86.94
8.75
8.54
8.68
8.71
8.79
0.00
18

11
Daniel Samohin
 Israel
170.75
89.03
81.72
8.32
7.75
8.32
8.18
8.29
0.00
8

12
Keegan Messing
 Canada
170.32
84.88
85.44
8.50
8.29
8.61
8.61
8.71
0.00
14

13
Dmitri Aliev
 Olympic Athletes from Russia
168.53
85.39
85.13
8.64
8.39
8.32
8.61
8.61
–2.00
19

14
Cha Jun-hwan
 South Korea
165.16
84.94
81.22
8.21
7.86
8.25
8.11
8.18
–1.00
13

15
Keiji Tanaka
 Japan
164.78
85.64
81.14
8.36
7.89
8.00
8.18
8.14
–2.00
5

16
Jorik Hendrickx
 Belgium
164.21
81.79
82.42
8.25
7.96
8.36
8.25
8.39
0.00
13

17
Misha Ge
 Uzbekistan
161.04
74.96
86.08
8.46
8.36
8.54
8.75
8.93
0.00
10

18
Michal Březina
 Czech Republic
160.92
76.58
84.34
8.57
8.21
8.39
8.57
8.43
0.00
17

19
Matteo Rizzo
 Italy
156.78
80.86
75.92
7.64
7.32
7.79
7.64
7.57
0.00
2

20
Deniss Vasiļjevs
 Latvia
155.06
76.42
80.64
8.14
7.86
7.96
8.18
8.18
–2.00
1

21
Brendan Kerry
 Australia
150.75
73.33
77.42
7.96
7.54
7.68
7.82
7.71
0.00
12

22
Paul Fentz
 Germany
139.82
66.98
72.84
7.50
7.14
7.14
7.39
7.25
0.00
3

23
Yan Han
 China
132.38
53.80
79.58
8.56
7.82
7.57
8.04
8.00
–1.00
4

24
Moris Kvitelashvili
 Georgia
128.01
63.35
70.66
7.34
6.86
6.68
7.32
7.04
–6.00
6

text:
Notes:
TSS - Total Segment Score; TES - Technical Element Score; PCS - Program Component Score
SS - Skating Skills; TR - Transitions; PE - Performance/Execution
CH - Choreography; IN - Interpretation; Ded - Deduction; StN - Starting Number

text: Overall[edit]

text: The skaters were ranked according to their overall score.[11]

text:
Rank
Name
Nation
TP
SP
FS

01 !
Yuzuru Hanyu
 Japan
317.85
111.68
1
206.17
2

02 !
Shoma Uno
 Japan
306.90
104.17
3
202.73
3

03 !
Javier Fernández
 Spain
305.24
107.58
2
197.66
4

4
Jin Boyang
 China
297.77
103.32
4
194.45
5

5
Nathan Chen
 United States
297.35
82.27
17
215.08
1

6
Vincent Zhou
 United States
276.69
84.53
12
192.16
6

7
Dmitri Aliev
 Olympic Athletes from Russia
267.51
98.98
5
168.53
13

8
Mikhail Kolyada
 Olympic Athletes from Russia
264.25
86.69
8
177.56
7

9
Patrick Chan
 Canada
263.43
90.01
6
173.42
8

10
Adam Rippon
 United States
259.36
87.95
7
171.41
10

11
Oleksii Bychenko
 Israel
257.01
84.13
13
172.88
9

12
Keegan Messing
 Canada
255.43
85.11
10
170.32
12

13
Daniel Samohin
 Israel
251.44
80.69
18
170.75
11

14
Jorik Hendrickx
 Belgium
248.95
84.74
11
164.21
16

15
Cha Jun-hwan
 South Korea
248.59
83.43
15
165.16
14

16
Michal Březina
 Czech Republic
246.07
85.15
9
160.92
18

17
Misha Ge
 Uzbekistan
244.94
83.90
14
161.04
17

18
Keiji Tanaka
 Japan
244.83
80.05
20
164.78
15

19
Deniss Vasiļjevs
 Latvia
234.58
79.52
21
155.06
20

20
Brendan Kerry
 Australia
233.81
83.06
16
150.75
21

21
Matteo Rizzo
 Italy
232.41
75.63
23
156.78
19

22
Paul Fentz
 Germany
214.55
74.73
24
139.82
22

23
Yan Han
 China
213.01
80.63
19
132.38
23

24
Moris Kvitelashvili
 Georgia
204.57
76.56
22
128.01
24

Did not advance to free skating

25
Julian Yee
 Malaysia

73.58
25

26
Chafik Besseghier
 France

72.10
26

27
Denis Ten
 Kazakhstan

70.12
27

28
Michael Christian Martinez
 Philippines

55.56
28

29
Felipe Montoya
 Spain

52.41
29

30
Yaroslav Paniot
 Ukraine

46.58
30

text: TP - Total points; SP - Short program; FS - Free skating